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COTI-2
go.drugbank.com/drugs/DB17507InvestigationalSynonyms: 1-piperazinecarbothioic acid, 4-(2-pyridinyl)-, 2-(6,7-dihydro-8(5h)-quinolinylidene)hydrazideHexapeptide-2
go.drugbank.com/drugs/DB18238ExperimentalSynonyms: Hexapeptide 2, L-lysinamide, l-histidyl-d-tryptophyl-l-alanyl-l-tryptophyl-d-phenylalanyl-Metoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalDiabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. … [A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GERD).
Synonyms: 2-methoxy-5-chloroprocainamide, 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamideMixtures: ESPAVEN MD, CLIFAR® GOTASCeftibuten
go.drugbank.com/drugs/DB01415ApprovedInvestigationalCeftibuten is a third-generation cephalosporin antibiotic that is orally-administered.
Mixtures: BUCEF PLUS 180/62.5 MG TOZ ICEREN SASE, 20 ADET, BUCEF PLUS 90/62.5 MG TOZ ICEREN SASE, 20 ADETCategories: Heterocyclic Compounds, 2-RingGuanethidine
go.drugbank.com/drugs/DB01170ApprovedWithdrawnAn antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepineph...
Synonyms: (2-(hexahydro-1(2h)-azocinyl)ethyl)guanidine, 2-(1-N,N-Heptamethyleneimino)ethylguanidineNialamide
go.drugbank.com/drugs/DB04820ApprovedWithdrawnWithdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Synonyms: 1-(2-(Benzylcarbamoyl)ethyl)-2-isonicotinoylhydrazine, 2-(2-(Benzylcarbamoyl)ethyl)hydrazide isonicotinic acidCategories: Heterocyclic Compounds, 1-RingCidofovir
go.drugbank.com/drugs/DB00369ApprovedInvestigationalCidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] I...
Categories: Heterocyclic Compounds, 1-RingSynonyms: (S)-(3-(4-amino-2-Oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid, ({[(S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acidEverolimus
go.drugbank.com/drugs/DB01590ApprovedInvestigationalIn a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and not on the mTORC2 protein. … Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor.
Synonyms: 42-O-(2-Hydroxyethyl)rapamycin, 40-O-(2-hydroxyethyl)-rapamycinCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexTocainide
go.drugbank.com/drugs/DB01056ApprovedWithdrawnAn antiarrhythmic agent which exerts a potential- and frequency-dependent block of sodium channels.
Categories: Antiarrhythmics, Class I, Cytochrome P-450 SubstratesSynonyms: 2-Amino-2',6'-propionoxylidide, 2-amino-N-(2,6-dimethylphenyl)propanamide