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Losartan
go.drugbank.com/drugs/DB00678ApprovedInvestigational[L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. … Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension.
Synonyms: (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol, 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazoleMixtures: EXPOPRESS® H, SATOREN ® H TABLETASRecifercept
go.drugbank.com/drugs/DB17899InvestigationalSynonyms: Recombinant human fibroblast growth factor receptor 3, Fibroblast growth factor receptor 3 (recombinant human soluble isoform ta-46)Ozekibart
go.drugbank.com/drugs/DB18675InvestigationalOzekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5). It is being investigated for the treatment of chondrosarcoma.
Synonyms: Immunoglobulin, anti-(human death receptor 5) (human-Lama glama clone IF5 single-domain VHH fragment) fusion protein with peptide linker (GGS)2 fusion protein with immunoglobulin anti-(human death receptor, Tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5).AVID-200
go.drugbank.com/drugs/DB18454InvestigationalAVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein.
Synonyms: Tgf-beta 1/3 inhibitor avid200, Tgf-.beta. ligand trap comprised of tgf-.beta. receptor ectodomains fused to a human fc domain (avid-200)Elivaldogene tavalentivec
go.drugbank.com/drugs/DB19095InvestigationalSynonyms: Dna (lentiviral vector clone lenti-d human x-linked adrenoleukodystrophy abcd1 gene cdna-specifying), A vsv-g*-pseudotyped self-inactivating hiv-1-derived lentiviral vector (plbp100 hald) encoding human adrenoleukodystrophy (ald) protein (abcd1 gene) under the control of a modified myeloproliferative sarcomaAAV2/8.TBG.hARSB
go.drugbank.com/drugs/DB17633InvestigationalSynonyms: Adeno-associated viral vector serotype 8 with liver-specific thyroxinebinding globulin (TBG) promoter driving the expression of the human ARSB gene, AAV2/8.TBG.hARSBMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigationalMetoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. … [A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527]
Mixtures: METOPROLOL HCT S 100/12.5, METOPROLOL HCT S 100/12.5Categories: Adrenergic beta-1 Receptor Antagonists, Cytochrome P-450 SubstratesAd-SGE-REIC
go.drugbank.com/drugs/DB17183InvestigationalSynonyms: REIC/Dkk-3 gene therapy, Ad5-SGE-REIC/Dkk-3Cinacalcet
go.drugbank.com/drugs/DB01012ApprovedInvestigationalCinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe.
Synonyms: (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine, N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amineCategories: Calcium-sensing Receptor Agonist, Increased Calcium-sensing Receptor SensitivityGoflikicept
go.drugbank.com/drugs/DB16396InvestigationalAcute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19)). … Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe
Synonyms: Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 receptor and a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein