Search

Displaying results 161 - 170 of 308 in total
  1. Drug

    Reposal

    go.drugbank.com/drugs/DB13805
    Experimental

    Reposal is a barbiturate derivative invented in the 1960s in Denmark that has sedative, hypnotic and anticonvulsant properties. It was used primarily in the treatment of insomnia.

  2. Drug

    Probucol

    go.drugbank.com/drugs/DB01599
    ApprovedInvestigationalWithdrawn

    A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).

  3. Drug

    Defibrotide

    go.drugbank.com/drugs/DB04932
    ApprovedInvestigational

    Defibrotide is the sodium salt of a mixture of single-stranded oligodeoxyribonucleotides derived from porcine mucosal DNA. It has been shown to have antithrombotic, anti-inflammatory and anti-ischemic properties (but without associated s...

  4. Drug

    Thalidomide

    go.drugbank.com/drugs/DB01041
    ApprovedInvestigationalWithdrawn

    A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of inflammatory disorders and cancers. Thal...

  5. Drug

    Iluzanebart

    go.drugbank.com/drugs/DB18275
    Investigational

    Synonyms: Immunoglobulin G1 [296-cysteine,301-glycine,306-cysteine], anti-(human triggering receptor expressed on myeloid cells 2) (human monoclonal VGL101 γ1-chain), disulfide with human monoclonal VGL101 κ-chain
  6. Drug

    Black cohosh

    go.drugbank.com/drugs/DB13975
    ApprovedInvestigational

    Black cohosh (Actaea racemosa or Cimicifuga racemosa), a member of the buttercup family, is a perennial plant which native to North America. Historical names for this plant include snakeroot, black bugbane, rattleweed, macrotys, and rheu...

  7. Drug

    Sabestomig

    go.drugbank.com/drugs/DB19326
    Investigational

    Sabestomig is under investigation in clinical trial NCT05216835 (Safety and Preliminary Efficacy Assessment of AZD7789 in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma).

    Synonyms: Immunoglobulin G1-kappa/lambda, anti-[Homo sapiens PDCD1 (programmed cell death 1, PD1, PD-1, CD279) and HAVCR2 (hepatitis A virus cellular receptor 2, T cell immunoglobulin and mucin domains family member
  8. Drug

    Fazpilodemab

    go.drugbank.com/drugs/DB18924
    Investigational

    Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis).

    Synonyms: Anti-fgfr1/klb mab, anti-KLB (1-450) [VH (Homo sapiens IGHV3-66*01 (
  9. Drug

    Talc

    go.drugbank.com/drugs/DB09511
    ApprovedInvestigational

    In fact, recent studies have reported that talc increases the risk of ovarian and endometrial cancers by approximately 30 percent.

  10. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    Approved

    Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation . Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass . Docusate ca...