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Melatonin
go.drugbank.com/drugs/DB01065ApprovedInvestigationalNutraceuticalVet approvedMelatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. … The pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone (hence the name), that is located in the center of the brain (rostro-dorsal to the superior colliculus
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesSynonyms: 5-methoxy-N-acetyl tryptamine, 5-methoxy-N-acetyltryptamineCefonicid
go.drugbank.com/drugs/DB01328ApprovedA second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. … It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-8-oxo-3-({[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid1-Naphthylamine-5-sulfonic acid
go.drugbank.com/drugs/DB07176ExperimentalSynonyms: 1-Amino-5-sulfonaphthalene, 1-Amino-5-naphthalenesufonic acid1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol))
go.drugbank.com/drugs/DB11331ApprovedWithdrawnPalmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as a surfactant [FDA Label].
Salts: 1-palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium saltSynonyms: PG(16:0/18:1), PG(16:0/18:1(9Z))Thymidine
go.drugbank.com/drugs/DB04485ApprovedInvestigational[A274683] While it lacks significant anti-tumor activity on its own,[A274688] it has been extensively investigated for nearly a decade as a biochemical modulator to enhance the efficacy and reduce the … toxicity of established anti-metabolite chemotherapeutic agents, such as 5-Fluorouracil (FU), Methotrexate (MTX), and Cytosine arabinoside (ara-C).
Synonyms: MT-1621 COMPONENT 2'-DEOXYTHYMIDINE, 1-(2-Deoxy-?-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedioneCategories: Heterocyclic Compounds, 1-RingChlorthalidone
go.drugbank.com/drugs/DB00310ApprovedInvestigationalChlorthalidone has been shown to have a number of pleiotropic effects that differentiate it from other diuretics such as [DB00999]. … These pathways may play a role in chlorthalidone's cardiovascular risk reduction effects.[A176330]
Mixtures: ATENOLOLO CLORTALIDONE EG, ATENOLOLO CLORTALIDONE EGCategories: Heterocyclic Compounds, 2-Ring1-Deoxy-Ribofuranose-5'-Phosphate
go.drugbank.com/drugs/DB03936ExperimentalSynonyms: 1-Deoxy-Ribofuranose-5'-PhosphateOfloxacin
go.drugbank.com/drugs/DB01165ApprovedInvestigationalA synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Categories: 4-Quinolones, Heterocyclic Compounds, 2-RingSynonyms: 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acidFinasteride
go.drugbank.com/drugs/DB01216ApprovedInvestigationalIt works in a similar fashion as [dutasteride], which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. … [L6244] Finasteride is commonly marketed under the brand names Propecia and Proscar to be used aloneo or in combination with [doxazosin], an alpha-blocker.
Synonyms: (5alpha,17beta)-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamideMixtures: Finasteride 0.1% / Minoxidil 5%, Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5%AKV-9
go.drugbank.com/drugs/DB18061ExperimentalSynonyms: 5-((S)-1-(3,5-bis(trifluoromethyl)phenoxy)ethyl)-3-hydroxycyclohex-2-en-1-one, 1,3-Cyclohexanedione, 5-[(1S)-1-[3,5-bis(trifluoromethyl)phenoxy]ethyl]-