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Mangafodipir
go.drugbank.com/drugs/DB06796ApprovedInvestigationalWithdrawnMangafodipir is a contrast agent used as a diagnostic tool administered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver and pancreas. … Teslascan has been removed from the Drug Product List by FDA in 2003, and withdrawn from the European market in 2012.
Products: TESLASCAN 0,01MMOL 50 ML FLAKON, 1 ADETMidodrine
go.drugbank.com/drugs/DB00211ApprovedInvestigationalAn ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSynonyms: 1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanolFerrous cation
go.drugbank.com/drugs/DB14510InvestigationalProducts: PLASTUFER 100 MG, PLASTUFER MITE 50 MGLevomethadone
go.drugbank.com/drugs/DB13515InvestigationalProducts: Levo-Methasan 10 mg-Tabletten, L-Polamidon 5 mg TablettenAntihemophilic factor (recombinant), PEGylated
go.drugbank.com/drugs/DB09329ApprovedInvestigationalwith at least one molecule of polyethylene glycol (MW 20 kDa) [FDA label]. … PEGylation is the covalent attachment of a polyethylene glycol polymer, called PEG, to a drug or protein.
Products: ADYNOVATE 500®IU / VIAL, ADYNOVATE 500 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTIONFenspiride
go.drugbank.com/drugs/DB08979InvestigationalFenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases. It is approved for use in Russia for the treatment of acute and chronic inflammatory diseases of ENT organs and the respirator...
Products: OXOFEN 2 MG/ML ŞURUP ,150 ML, PASFEN 2MG/ML ŞURUPEncorafenib
go.drugbank.com/drugs/DB11718ApprovedInvestigationalapproved encorafenib and [binimetinib] (BRAFTOVI and MEKTOVI, Array BioPharma Inc.) in combination for patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, as detected by
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: BRAFTOVI® 75 MG CÁPSULAS, BRAFTOVİ 75 MG SERT KAPSÜL, 42 ADETDeucravacitinib
go.drugbank.com/drugs/DB16650ApprovedInvestigational[A246943] Deucravacitinib was first approved by the FDA in September 2022 to treat moderate-to-severe plaque psoriasis. … to this therapeutic target.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: SOTYKTU 6 mg film coated tablets, SOTYKTU® 6MG TABLETAS RECUBIERTASLenacapavir
go.drugbank.com/drugs/DB15673ApprovedInvestigational[A244170, A244175, A244180, A244190] Lenacapavir was first globally approved on August 22, 2022 by the European Commission to treat adults with multi-drug resistant HIV infection. … HIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens
Synonyms: N-((1S)-1-(3-(4-CHLORO-3-((METHYLSULFONYL)AMINO)-1-(2,2,2-TRIFLUOROETHYL)-1H-INDAZOL-7-YL)-6-(3-METHYL-3-(METHYLSULFONYL)-1-BUTYN-1-YL)-2-PYRIDINYL)-2-(3,5-DIFLUOROPHENYL)ETHYL)-5,5-DIFLUORO-3B,4,4A,5-, METHANESULFONAMIDO)-1-(2,2,2-TRIFLUOROETHYL)-1H-INDAZOL-7-YL)-6-(3-(METHANESULFONYL)-3-METHYLBUT-1-YN-1-YL)PYRIDIN-2-YL)-2-(3,5- DIFLUOROPHENYL)ETHYL)-2-((3BS,4AR)-5,5-DIFLUORO-3-(TRIFLUOROMETHYL)-3B,4,4A,5-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsCarisoprodol
go.drugbank.com/drugs/DB00395Approvedfor abuse in addition to a low risk of dependence [L5074]. … In January 2012, this drug was classified as a Schedule IV substance under the controlled substances act in several US states due to alarming rates of abuse [A176062, A176077] despite having a low potential
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesProducts: Carisoprodol Tablets, USP, 350 mg