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Ombitasvir
go.drugbank.com/drugs/DB09296ApprovedInvestigationalOmbitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesParitaprevir
go.drugbank.com/drugs/DB09297ApprovedInvestigationalParitaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that ...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesTenofovir alafenamide
go.drugbank.com/drugs/DB09299ApprovedInvestigationalTenofovir alafenamide is a novel tenofovir prodrug developed in order to improve renal safety when compared to the counterpart tenofovir disoproxil. Both of these prodrugs were first created to cover the polar phosphonic acid group on te...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSolithromycin
go.drugbank.com/drugs/DB09308InvestigationalSolithromycin is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired pneumonia (CAP) and other infections.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesTegafur-uracil
go.drugbank.com/drugs/DB09327ApprovedTegafur-uracil is an anti-tumor compound containing tegafur (1-(2-tetrahydrofuryl)-5-fluorouracil) and uracil in a molar ratio of 1:4. It was developed as an anti-cancer therapy by Taiho Pharmaceutical Co Ltd. It is approved in different...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesPiperonyl butoxide
go.drugbank.com/drugs/DB09350ApprovedVet approvedPiperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is used for the treatment of head, pubic (crab), and body lice. Piperonyl butoxide is a synergist. It has no pesticidal activity of its own...
Mixtures: KWELL-P %0,3 + %3 MEDİKAL ŞAMPUAN, 60 ML, KWELL-P %0,3 + %3 MEDİKAL ŞAMPUAN, 120 MLCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP3A InhibitorsLevobetaxolol
go.drugbank.com/drugs/DB09351ApprovedLevobetaxolol is a beta-blocker used to lower the pressure in the eye to treat conditions such as glaucoma. It was marketed as a 0.5% ophthalmic solution of levobetaxolol hydrochloride under the trade name Betaxon but has been discontinued.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesFluprednisolone
go.drugbank.com/drugs/DB09378ApprovedA synthetic glucocorticoid with anti-inflammatory properties.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEsterified estrogens
go.drugbank.com/drugs/DB09381ApprovedEsterified estrogens contain a mixture of estrogenic substances; the principle component is estrone. Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that the total is not <90%. Esterifi...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMeprednisone
go.drugbank.com/drugs/DB09383ApprovedCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers