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Gam-COVID-Vac
go.drugbank.com/drugs/DB15848Investigational-2 spike glycoprotein. … Preliminary results suggested that all participants developed antibodies to the SARS-CoV-2 glycoproteins with a good safety profile in both trials.
Synonyms: Sputnik VSARS-CoV-2 Sclamp
go.drugbank.com/drugs/DB15849InvestigationalPreclinical trials showed the vaccine candidate produced high levels of neutralizing antibodies, and induced a strong T-cell response. … The University of Queensland (UQ), in partnership with The Coalition for Epidemic Preparedeness Inovations (CEPI) and CSL has developed a COVID-19 candidate, SARS-CoV-2 Sclamp.
Synonyms: UQ-1-SARS-CoV-2-Sclamp, SARS-CoV-2 Sclamp adjuvanted vaccineIMM-101
go.drugbank.com/drugs/DB15850InvestigationalIMM-101 is a heat-inactivated immune-activating mycobacterial product. … As of July 2020, researchers from the Ottawa Hospital and Queen’s University, in partnership with the Canadian Cancer Society-funded Canadian Cancer Trials Group (CCTG), are conducting a trial in over
Coronavirus-Like Particle COVID-19 Vaccine
go.drugbank.com/drugs/DB15852ExperimentalA Phase 1 clinical trial was launched in July 2020 evaluating the safety, tolerability, and immunogenicity of this vaccine candidate with or without either Cpg 1018 or AS03 (NCT04450004) in adults aged … The vaccine was developed by creating SARS-Cov-2 virus-like particles (CoVLPs), which mimic the structure of the virus without carrying the genetic components required for infection.
RUTI® Vaccine
go.drugbank.com/drugs/DB15853InvestigationalMuch like the BCG vaccine, the RUTI® vaccine is also being tested as a prophylactic for SARS-CoV2. … Sponsored by Fundació Institut Germans Trias i Pujol, the RUTI® Vaccine is being tested for prevention of COVID-19 infection in a controlled trial with 315 healthcare worker participants (NCT04453488).
ARCoV
go.drugbank.com/drugs/DB15855ExperimentalSARS-CoV-2 mRNA vaccine (ARCoV) is a novel mRNA coronavirus vaccine that consists of a lipid nanoparticle-encapsulated mRNA encoding the receptor binding domain of SARS-CoV-2[A220048]. … Manufactured as a liquid, ARCoV is thermostable at room temperature for at least 1 week.
Autologous Non-Hematopoietic Peripheral Blood Stem Cells
go.drugbank.com/drugs/DB15867InvestigationalAutologous non-hematopoietic peripheral blood stem cells have been created into a formulation for use in a clinical trial (NCT04473170) by the Abu Dhabi Stem Cells Center. … The cells have the characterizations of CD90+, CD133+, Oct-4+, CD45-, and CD71-.[L16363]
Methylisothiazolinone
go.drugbank.com/drugs/DB15884InvestigationalSynonyms: 2-Methyl-4-isothiazolin-3-one, 2-Methyl-4-isothiazoline-3-oneCategories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting