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Dibromothymoquinone
go.drugbank.com/drugs/DB04646ExperimentalAt higher concentrations, it acts as an electron acceptor, intercepting electrons either before or at the site of its inhibitory activity. [PubChem]
Piritramide
go.drugbank.com/drugs/DB12492ApprovedWithdrawnPiritramide has been investigated for the supportive care of Pain, Postoperative and Postoperative Nausea and Vomiting.
NOX-700
go.drugbank.com/drugs/DB05464ExperimentalIt has since been found that oxidative signaling of the redox-sensitive transcription factor, NF-κB, and inhibiting protein glycation are responsible for the drug's therapeutic effects.
Pyridoxal phosphate
go.drugbank.com/drugs/DB00114ApprovedInvestigationalNutraceuticalThis is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is tra...
Zebularine
go.drugbank.com/drugs/DB03068ExperimentalIt acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates.
Prolectin-M
go.drugbank.com/drugs/DB16521InvestigationalProlectin-M is a (1-6)-alpha-D-mannopyranose[L31338] and acts as an antagonist of galectin.
Celiprolol
go.drugbank.com/drugs/DB04846ApprovedInvestigationalWithdrawnCeliprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris. It is simultaneously a selective β1 receptor antagonist, a β2 receptor partial agonist and a weak α2 receptor antagonist. In ...
Edrophonium
go.drugbank.com/drugs/DB01010ApprovedIt has also been used as an antidote to curare principles.
Fursultiamine
go.drugbank.com/drugs/DB08966ApprovedIt has also been suggested for several non-deficiency disorders but has not yet proven useful. Fursultiamine is a vitamin B1 derivative.
Darunavir
go.drugbank.com/drugs/DB01264ApprovedInvestigationalDarunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to...