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Displaying results 1741 - 1750 of 10000 in total
  1. Drug

    Carprazidil

    go.drugbank.com/drugs/DB21012
    Experimental

    Carprazidil is a small molecule drug. The usage of the INN stem '-dil' in the name indicates that Carprazidil is a vasodilator. Carprazidil has a monoisotopic molecular weight of 291.1 Da.

  2. Drug

    Biclodil

    go.drugbank.com/drugs/DB21180
    Experimental

    Biclodil is a small molecule drug. The usage of the INN stem '-dil' in the name indicates that Biclodil is a vasodilator. Biclodil has a monoisotopic molecular weight of 246.01 Da.

  3. Drug

    Sinitrodil

    go.drugbank.com/drugs/DB21396
    Experimental

    Sinitrodil is a small molecule drug. The usage of the INN stem '-dil' in the name indicates that Sinitrodil is a vasodilator. Sinitrodil has a monoisotopic molecular weight of 238.06 Da.

  4. Drug

    DT-DEC01

    go.drugbank.com/drugs/DB19433
    Experimental

    DT-DEC01 is a novel Dystrophin Expressing Chimeric (DEC) cell therapy being investigated by Dystrogen Therapeutics Corporation.

  5. Drug

    Valrubicin

    go.drugbank.com/drugs/DB00385
    Approved

    It is a semisynthetic analog of the [doxorubicin], which is an anthracycline drug. Used in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder. … Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the trade name VALSTAR.

    Categories: Topoisomerase II Inhibitors
  6. Drug

    Zoliflodacin

    go.drugbank.com/drugs/DB12817
    ApprovedInvestigational

    [A275268] Zoliflodacin is a first-in-class spiropyrimidinetrione antibiotic designed to address this need by inhibiting bacterial type II topoisomerases (DNA gyrase and topoisomerase IV), thereby blocking … FDA in December 2025, following Fast Track, Qualified Infectious Disease Product, and Priority Review designations.[L54743,L54803]

    Categories: Topoisomerase II Inhibitors
  7. Drug

    Somatrem

    go.drugbank.com/drugs/DB09098
    ApprovedWithdrawn

    continues to be mired in persistent bioethical debate [A32292]. … Despite the ability of almost all contemporary recombinant growth hormones to cause definite and demonstrable increases in growth rate in patients who are administered the drug, the use of these agents

    Mixtures: Protropin Inj Pws 10mg/vial, Protropin - Kit Im Sc 10mg/vial
  8. Drug

    Sparfloxacin

    go.drugbank.com/drugs/DB01208
    ApprovedWithdrawn

    DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription. … Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase.

    Categories: Topoisomerase II Inhibitors
  9. Drug

    Magnesium carbonate

    go.drugbank.com/drugs/DB09481
    Approved

    Magnesium carbonate, also known as magnesite, is a common over the counter remedy for heartburn and upset stomach caused by overproduction of acid in the stomach [FDA Label].

    Mixtures: Dol Mite Tab, Mag/cal 1:1 Capsules W Vitamin DCategories: Compounds used in a research, industrial, or household setting
  10. Drug

    Gemifloxacin

    go.drugbank.com/drugs/DB01155
    ApprovedInvestigational

    It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are essential for bacterial growth. … Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia.

    Categories: Topoisomerase II Inhibitors