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Pegzilarginase
go.drugbank.com/drugs/DB14780ApprovedPegzilarginase is a recombinant, cobalt-substituted, and pegylated human arginase 1 enzyme therapy designed to address the underlying metabolic deficit in arginase 1 deficiency (ARG1-D). … FDA in February 2026 for the treatment of hyperargininemia in adult and pediatric patients aged 2 years and older with ARG1-D, to be used in conjunction with dietary protein restriction.
Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismSynonyms: Optimised human arginase I, Co-ArgI-PEG modified human arginase IFepixnebart
go.drugbank.com/drugs/DB19079InvestigationalFepixnebart is under investigation in clinical trial NCT04456686 (Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Osteoarthritis).
Synonyms: Ly3016859 (humanized monoclonal antibody to human tgf.alpha. and epiregulin), IMMUNOGLOBULIN G4 (226-PROLINE,232-ALANINE,233-ALANINE,DE-C-TERMINAL-LYSINE), ANTI-(HUMAN EPIREGULIN AND TRANSFORMING GROWTH FACTOR .ALPHA.)Infliximab
go.drugbank.com/drugs/DB00065ApprovedInvestigationalInfliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions [A31469]. … In clinical trials, multiple infusions of infliximab displayed in a reduction of signs and symptoms of inflammatory diseases and induction of remission in patients who have had an inadequate response to
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: IMMUNOGLOBULIN G (HUMAN-MOUSE MONOCLONAL CA2 HEAVY CHAIN ANTI-HUMAN TUMOR NECROSIS FACTOR), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL CA2 LIGHT CHAIN, DIMERDazodalibep
go.drugbank.com/drugs/DB19025InvestigationalDazodalibep is under investigation in clinical trial NCT06104124 (A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic
Synonyms: THIRD FIBRONECTIN TYPE III DOMAIN (HUMAN, PROTEIN VIB4920 (RECOMBINANT HUMAN TENASCIN C CD40 LIGAND-BINDING THIRD FIBRONECTIN TYPE III DOMAIN) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 19-AMINO ACID LINKER) FUSION PROTEIN WITH TENASCIN C CD40 LIGAND-BINDINGElosulfase alfa
go.drugbank.com/drugs/DB09051ApprovedInvestigationalElosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™.
Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismSynonyms: Recombinant human N-acetylgalactosamine-6-sulfatase, Recombinant human N-acetylgalactosamine-6-sulfatase (rhGALNS)CAM-GM201
go.drugbank.com/drugs/DB17687ExperimentalSynonyms: Recombinant adeno-associated viral vector serotype 2/1 encoding human beta-hexosaminidase alpha and beta subunits, rAAV2/1 Hex alpha and betaHemoglobin glutamer-256 (human)
go.drugbank.com/drugs/DB19285InvestigationalHemoglobin glutamer-256 (human) is under investigation in clinical trial NCT00076648 (Safety and Efficacy of Polyheme(r) in Hemorrhagic Shock Following Traumatic Injuries Beginning in the Pre-hospital
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsSynonyms: Hemoglobin glutamer-256 (human), Polymerized human hemoglobin (pyridoxylated)Recombinant human plasma gelsolin
go.drugbank.com/drugs/DB15746InvestigationalPlasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues.
Categories: Amino Acids, Peptides, and Proteins, Intracellular Signaling Peptides and ProteinsSynonyms: Recombinant human gelsolinPorphobilinogen deaminase, human recombinant
go.drugbank.com/drugs/DB17674InvestigationalSynonyms: Porphobilinogen deaminase, human recombinant, Recombinant human porphobilinogen deaminaseHuman glial progenitor cells
go.drugbank.com/drugs/DB18265InvestigationalSynonyms: Human glial progenitor cells