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Displaying results 171 - 180 of 10139 in total
  1. Drug

    Infliximab

    go.drugbank.com/drugs/DB00065
    ApprovedInvestigational

    Infliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions [A31469]. … In clinical trials, multiple infusions of infliximab displayed in a reduction of signs and symptoms of inflammatory diseases and induction of remission in patients who have had an inadequate response to

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: IMMUNOGLOBULIN G (HUMAN-MOUSE MONOCLONAL CA2 HEAVY CHAIN ANTI-HUMAN TUMOR NECROSIS FACTOR), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL CA2 LIGHT CHAIN, DIMER
  2. Drug

    Dazodalibep

    go.drugbank.com/drugs/DB19025
    Investigational

    Dazodalibep is under investigation in clinical trial NCT06104124 (A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic

    Synonyms: THIRD FIBRONECTIN TYPE III DOMAIN (HUMAN, PROTEIN VIB4920 (RECOMBINANT HUMAN TENASCIN C CD40 LIGAND-BINDING THIRD FIBRONECTIN TYPE III DOMAIN) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 19-AMINO ACID LINKER) FUSION PROTEIN WITH TENASCIN C CD40 LIGAND-BINDING
  3. Drug

    Mecasermin

    go.drugbank.com/drugs/DB01277
    ApprovedInvestigational

    IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. … The amino acid sequence of the product is identical to that of endogenous human IGF-1.

    Synonyms: Human somatomedin C, INSULIN-LIKE GROWTH FACTOR I (HUMAN)Categories: Human Insulin-like Growth Factor Analogs, Recombinant Human Insulin-like Growth Factor-1
  4. Drug

    Elosulfase alfa

    go.drugbank.com/drugs/DB09051
    ApprovedInvestigational

    Elosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™.

    Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismSynonyms: Recombinant human N-acetylgalactosamine-6-sulfatase, Recombinant human N-acetylgalactosamine-6-sulfatase (rhGALNS)
  5. Drug

    Eurotium amstelodami

    go.drugbank.com/drugs/DB15526
    Approved

    Eurotium amstelodami allergenic extract is used in allergenic testing.

    Synonyms: Molds, rusts and smuts, aspergillus amsterdami
  6. Drug

    CAM-GM201

    go.drugbank.com/drugs/DB17687
    Experimental

    Synonyms: Recombinant adeno-associated viral vector serotype 2/1 encoding human beta-hexosaminidase alpha and beta subunits, rAAV2/1 Hex alpha and beta
  7. Drug

    Hemoglobin glutamer-256 (human)

    go.drugbank.com/drugs/DB19285
    Investigational

    Hemoglobin glutamer-256 (human) is under investigation in clinical trial NCT00076648 (Safety and Efficacy of Polyheme(r) in Hemorrhagic Shock Following Traumatic Injuries Beginning in the Pre-hospital

    Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsSynonyms: Hemoglobin glutamer-256 (human), Polymerized human hemoglobin (pyridoxylated)
  8. Drug

    Recombinant human plasma gelsolin

    go.drugbank.com/drugs/DB15746
    Investigational

    Plasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues.

    Categories: Amino Acids, Peptides, and Proteins, Intracellular Signaling Peptides and ProteinsSynonyms: Recombinant human gelsolin
  9. Drug

    Interleukin-12 human recombinant

    go.drugbank.com/drugs/DB19299
    Investigational

    Synonyms: Human interleukin 12 recombinant, Human interleukin-12 recombinant
  10. Drug

    Porphobilinogen deaminase, human recombinant

    go.drugbank.com/drugs/DB17674
    Investigational

    Synonyms: Porphobilinogen deaminase, human recombinant, Recombinant human porphobilinogen deaminase