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Displaying results 171 - 180 of 10000 in total
  1. Drug

    Finasteride

    go.drugbank.com/drugs/DB01216
    ApprovedInvestigational

    It works in a similar fashion as [dutasteride], which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. … [L6244] Finasteride is commonly marketed under the brand names Propecia and Proscar to be used aloneo or in combination with [doxazosin], an alpha-blocker.

    Mixtures: Finasteride 0.1% / Minoxidil 5%, Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5%Categories: 5-alpha Reductase Inhibitors, Cytochrome P-450 Substrates
  2. Drug

    Flucytosine

    go.drugbank.com/drugs/DB01099
    ApprovedInvestigational

    A fluorinated cytosine analog that is used as an antifungal agent.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-FC, 5-Fluorocytosine
  3. Drug

    Methyltestosterone

    go.drugbank.com/drugs/DB06710
    ApprovedInvestigational

    A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. … Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US.

    Categories: 3-Oxoandrosten (4) Derivatives, Cytochrome P-450 SubstratesSynonyms: 17-beta-Hydroxy-17-methylandrost-4-en-3-one, 17beta-Hydroxy-17-methylandrost-4-en-3-one
  4. Drug

    Zavegepant

    go.drugbank.com/drugs/DB15688
    ApprovedInvestigational

    of oral zavegepant (150 mg bid) in subjects with mild allergic asthma. … Zavegepant is a third-generation CGRP receptor antagonist that is small in size and highly soluble. Due to its pharmacological properties, it can be administered intranasally.

    Categories: MATE 1 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 1-piperidinecarboxamide, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-n-((1r)-1-((7-methyl-1h-indazol-5-yl)methyl)-2-(4-(1-methyl-4-piperidinyl)-1-piperazinyl)-2-oxoethyl)-
  5. Drug

    Ertugliflozin

    go.drugbank.com/drugs/DB11827
    ApprovedInvestigational

    Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus. … [A31581] Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.[L48621]

    Mixtures: สเตกกลูแจน (15 มิลลิกรัม/100 มิลลิกรัม), สเตกกลูแจน (15 มิลลิกรัม/100 มิลลิกรัม)Categories: P-glycoprotein substrates, Sodium-Glucose Transporter 2 Inhibitors
  6. Drug

    Phenobarbital

    go.drugbank.com/drugs/DB01174
    ApprovedInvestigational

    A barbituric acid derivative that acts as a nonselective central nervous system depressant. … It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.

    Mixtures: PIROFEN 200 MG/15 MG SUPPOZITUAR, 5 ADET, PIROFEN 200 MG/15 MG SUPPOZITUAR, 50 ADETCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substrates with a Narrow Therapeutic Index
  7. Drug

    Cholesteryl Linoleate

    go.drugbank.com/drugs/DB02092
    Experimental

    Synonyms: (3β)-cholest-5-en-3-ol, (Z,Z)-9,12-octadecadienoate, cholest-5-en-3β-yl (Z,Z)-octadeca-9,12-dienoate
  8. Drug

    Leucovorin

    go.drugbank.com/drugs/DB00650
    ApprovedInvestigational

    [L56091, L56092] Additionally, it is used in combination with 5-fluorouracil (5-FU) to enhance therapeutic efficacy in the palliative treatment of advanced colorectal cancer and to treat megaloblastic … Leucovorin, also known as folinic acid or citrovorum factor, is a reduced form of folic acid that serves as a vital coenzyme in nucleic acid synthesis.

    Mixtures: FERPLEX FOL 40 MG + 0.185 MG/15 ML ORAL ÇÖZELTİ, 10 ADET, KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 10 FLK.Categories: Compounds used in a research, industrial, or household setting, Vitamin B Complex
  9. Drug

    6-(3',5'-DIMETHYLBENZYL)-1-ETHOXYMETHYL-5-ISOPROPYLURACIL

    go.drugbank.com/drugs/DB07820
    Experimental

    Synonyms: 6-(3',5'-DIMETHYLBENZYL)-1-ETHOXYMETHYL-5-ISOPROPYLURACIL
  10. Drug

    Prasterone sulfate

    go.drugbank.com/drugs/DB05804
    Investigational

    DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin. DHEA-S is elevated with hyperprolactinemia.

    Synonyms: (3-beta)-3-(Sulfooxy)androst-5-en-17-one, 17-Ketoandrost-5-en-3beta-yl sulfateCategories: Cytochrome P-450 CYP3A7 Substrates, 17-Ketosteroids