Prasterone sulfate

DB05804InvestigationalSmall molecule

DHEA sulfate is the major steroid of the fetal adrenal. DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin. DHEA-S...

Chemical structure of Prasterone sulfate
Mechanism
Curator reviewed
Primary indication
Investigated for use/treatment in asthma and burns and burn infections.Curator reviewed
Formula / weight
C19H28O5S · 368.488 g/mol (avg)
Also known as
Dehydroepiandrosterone monosulfate · Dehydroepiandrosterone sulfate · Dehydroepiandrosterone sulphate · Dehydroisoandrosterone sulfate · DHEA sulfate

Resolves to

Structure
InChIKeyCZWCKYRVOZZJNM-USOAJAOKSA-NSMILES[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OS(O)(=O)=O

What you can answer from here — as of September 13, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
10TransportersSubstrate / inhibitor direction, not just membership
Listed above
247Drug interactionsStructured to mechanism, not free text
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1Clinical trialPhase, status and sponsor resolved per trial
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25+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Prasterone sulfate, and which of those have an active Phase 3 trial?

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