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DHEA sulfate is the major steroid of the fetal adrenal. DHEA-S is the principal adrenal androgen and is secreted together with cortisol under the control of ACTH and prolactin. DHEA-S...
- Mechanism
- Curator reviewed
The low levels of dehydroepiandrosterone sulfate(DHEA-S)is associated with unfavorable levels of several strong cardiovascular disease risk factors, such as lipids and blood pleasure, which are components of the metabolic syndrome, and insulin levels. DHEA-S deficiency is risk factors of obesity and insulin resistance, but it is not clear, whether this possible influence is independent.
- Primary indication
- Investigated for use/treatment in asthma and burns and burn infections.Curator reviewed
- Formula / weight
- C19H28O5S · 368.488 g/mol (avg)
- Also known as
- Dehydroepiandrosterone monosulfate · Dehydroepiandrosterone sulfate · Dehydroepiandrosterone sulphate · Dehydroisoandrosterone sulfate · DHEA sulfate
Resolves to
CZWCKYRVOZZJNM-USOAJAOKSA-NSMILES[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OS(O)(=O)=OWhat you can answer from here — as of September 13, 2026
Which drugs share a target with Prasterone sulfate, and which of those have an active Phase 3 trial?