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Filibuvir
go.drugbank.com/drugs/DB11878InvestigationalFilibuvir has been used in trials studying the treatment of Hepatitis, Hepatitis C, and Chronic Hepatitis C.
Categories: Heterocyclic Compounds, 1-RingLuminespib
go.drugbank.com/drugs/DB11881InvestigationalAUY922 has been used in trials studying the treatment of Lymphoma, Breast Cancer, Metastatic Disease, Advanced Solid Tumors, and Hematologic Neoplasms, among others.
Categories: Heterocyclic Compounds, 1-RingAnlotinib
go.drugbank.com/drugs/DB11885InvestigationalAnlotinib has been investigated for the treatment of Non-small Cell Lung Cancer and Metastatic Colorectal Cancer.
Synonyms: 1-((4-(4-fluoro-2-methyl-1h-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropan-amineCategories: Heterocyclic Compounds, 2-RingFimepinostat
go.drugbank.com/drugs/DB11891InvestigationalFimepinostat (CUDC-907) has been used in trials studying the treatment of lymphoma, solid tumors, breast cancer, multiple myeloma, and NUT midline carcinoma, among others.
Synonyms: 5-pyrimidinecarboxamide, N-hydroxy-2-[[[2-(6-methoxy-3-pyridinyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]methylamino]-, N-hydroxy-2-(((2-(6-methoxypyridin-3-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)(methyl)amino)pyrimidine-5-carboxamideCategories: Heterocyclic Compounds, 1-Ring, Phosphatidylinositol 3-Kinases, antagonists & inhibitorsEfatutazone
go.drugbank.com/drugs/DB11894InvestigationalEfatutazone has been used in trials studying the treatment of Lymphoma, Liposarcoma, Solid Tumors, Multiple Myeloma, and Recurrent Thyroid Cancer, among others.
Categories: Heterocyclic Compounds, 1-Ring2,4-thiazolidinedione
go.drugbank.com/drugs/DB11898InvestigationalThiazolidinedione has been investigated for the treatment of Type 2 Diabetes, Diabetes Mellitus, and DIABETES MELLITUS, TYPE 2.
Categories: Heterocyclic Compounds, 1-RingTimapiprant
go.drugbank.com/drugs/DB11900InvestigationalOC000459 is under investigation for the treatment of Severe Eosinophilic Asthma. OC000459 has been investigated for the treatment of Bronchial Asthma.
Categories: Heterocyclic Compounds, 2-RingApalutamide
go.drugbank.com/drugs/DB11901ApprovedInvestigationalIn a randomized trial, the median metastasis-free survival for patients taking apalutamide was 40.5 months compared to 16.2 months for patients taking a placebo [L1295]. … In a phase-2 multicenter open-label study, 89% of patients with non-metastatic, castration-resistant prostate cancer had ≥50% PSA decline at week 12 of apalutamide treatment [A31846].
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsProducts: ERLEADA ®TABLETAS RECUBIERTAS 60 MGRociletinib
go.drugbank.com/drugs/DB11907InvestigationalRociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer.
Categories: Heterocyclic Compounds, 1-RingLebrikizumab
go.drugbank.com/drugs/DB11914ApprovedInvestigationalThis approval is based on the positive results obtained from the Phase 3 studies ADvocate 1 and ADvocate 2, where nearly 80% of patients taking lebrikizumab either as monotherapy or combination therapy … Lebrikizumab is a monoclonal antibody that binds to IL-13 with high affinity and slow off-rate.[L51374] It binds to a different epitope compared [tralokinumab].