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COVID19 s-vax loaded autologous dendritic cell vaccine
go.drugbank.com/drugs/DB15814ExperimentalThe rationale is that loading a DC cell with SARS-Cov-2 antigens and administering it as a vaccine can induce a more prolific immune response. … DC-based vaccines are currently used in cancer therapeutics, and are being tested for COVID-19.
Prenylamine
go.drugbank.com/drugs/DB04825ApprovedWithdrawnPrenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Categories: Vasodilators Used in Cardiac DiseasesSynonyms: DL-prenylamine, N-(3,3-Diphenylpropyl)-alpha-methylphenaethylaminLoxapine
go.drugbank.com/drugs/DB00408ApprovedInvestigationalAn antipsychotic agent used in schizophrenia. [PubChem]
Categories: Dopamine D2 Receptor AntagonistsAd5-nCoV
go.drugbank.com/drugs/DB15655InvestigationalAd5-nCoV is a recombinant adenovirus type-5 vector (Ad5) vaccine currently being investigated for prophylaxis against SARS-CoV-2. … )[L12675] with an expected completion in December 2020.
Miglitol
go.drugbank.com/drugs/DB00491ApprovedMiglitol should be taken at the start of a meal for maximal effect and the effect will depend on the amount of poly and oligosaccharides in the diet. … It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing the digestion of carbohydrates (such as disaccharides, oligosaccharides, and polysaccharides) into
Categories: Drugs Used in DiabetesTetrofosmin
go.drugbank.com/drugs/DB11180ApprovedTetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.[A7788]
Mixtures: Tetrofosmin ROTOP 0,23 mg Kit für ein radioaktives ArzneimittelTenapanor
go.drugbank.com/drugs/DB11761ApprovedInvestigationala novel alternative in the treatment of IBS-C. … [L8558] It was first designed and synthesized in 2012.
Insulin icodec
go.drugbank.com/drugs/DB16693ApprovedInvestigational[L51078]The US FDA subsequently approved insulin icodec in March 2026 for use as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. [L56102] … Insulin icodec is an ultra long-acting basal insulin analogue.
Categories: Drugs Used in DiabetesEcallantide
go.drugbank.com/drugs/DB05311ApprovedApart from its FDA and EMA indication, ecallantide has been used off label in the management of nonhistaminergic angioedema, not due to HAE [A32017]. … By reversibly binding to plasma kallikrein, ecallantide displays a rapid on-rate and a slow off-rate that results in high affinity inhibition in the picomolar range [L1458].
Categories: Drugs Used in Hereditary AngioedemaMafenide
go.drugbank.com/drugs/DB06795ApprovedVet approvedWithdrawnIn November 2022, the use of mafenide acetate (powder for 5% topical solution) was withdrawn by the FDA due to an unresolved confirmatory study required to fulfill the accelerated approval requirements … [L36773] In 1998, mafenide acetate was approved under the FDA’s accelerated approval regulations.