Search

Displaying results 1801 - 1810 of 10000 in total
  1. Drug

    Zopiclone

    go.drugbank.com/drugs/DB01198
    ApprovedInvestigational

    Zopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylate
  2. Drug

    Amiloride

    go.drugbank.com/drugs/DB00594
    ApprovedInvestigational

    A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. … This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct.

    Mixtures: Riva-amilzide 5/50 mg, Nu-amilzide 5/50 Mg TabCategories: Decreased Renal K+ Excretion, Heterocyclic Compounds, 1-Ring
  3. Drug

    Tezacitabine

    go.drugbank.com/drugs/DB06433
    Investigational

    A synthetic purine nucleoside analogue with potential antineoplastic activity.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2'-Deoxy-2'-(fluoromethylene)cytidine
  4. Drug

    o-Bromophenol

    go.drugbank.com/drugs/DB04586
    Experimental

    Synonyms: 2-Bromfenol, 2-Bromophenol
  5. Drug

    Tuaminoheptane

    go.drugbank.com/drugs/DB13238
    Experimental

    Tuaminoheptane is a sympathomimetic drug typically used as a nasal decongestant.[A198534,A275018]

    Synonyms: 2-Heptanamine, 2-Aminoheptane
  6. Drug

    AL-01211

    go.drugbank.com/drugs/DB17654
    Investigational

    Synonyms: N-[(1R,2R)-2-(3-chloro-4-cyclopropoxyphenyl)-2-hydroxy-1-(pyrrolidinylmethyl)ethyl]-2-(6-chloro(2-naphthyl))-2-(hydroxyimino)acetamide
  7. Drug

    beta-D-Galactosamine

    go.drugbank.com/drugs/DB02678
    Experimental

    Synonyms: 2-amino-2-deoxy-β-D-galactopyranose, 2-deoxy-2-aminogalactose
  8. Drug

    Janssen COVID-19 Vaccine

    go.drugbank.com/drugs/DB15857
    ApprovedInvestigational

    SARS-COV-2 challenge. … A preclinical study in hamsters infected with SARS-COV-2 infection[A220053] showed a single immunization with the vaccine-elicited neutralizing responses and protected against SARS-CoV-2 induced pneumonia

    Synonyms: Adenovirus type 26 encoding SARS-COV-2 spike glycoprotein, Ad26.COV2.S
  9. Drug

    Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine

    go.drugbank.com/drugs/DB16757
    Approved

    [L40694] It is composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion conformation) and is mixed with the AS03 adjuvant system prior to administration. … [A245819] Plant-based VLPs offer a number of advantages as compared to other vaccine platforms, including speed and ease of manufacturing and increased immunogenicity.

    Synonyms: Recombinant SARS-CoV-2 spike (S)-protein virus-like particle
  10. Drug

    LCL-161

    go.drugbank.com/drugs/DB12085
    Investigational

    LCL161 has been used in trials studying the treatment of Leukemia, Neoplasms, Solid Tumors, Breast Cancer, and Ovarian Cancer, among others.

    Synonyms: (2S)-N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamideCategories: Proto-Oncogene Proteins c-bcl-2, antagonists & inhibitors, Heterocyclic Compounds, 1-Ring