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Displaying results 1811 - 1820 of 10000 in total
  1. Drug

    Dacomitinib

    go.drugbank.com/drugs/DB11963
    ApprovedInvestigational

    Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible

    Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic Index
  2. Drug

    SJG-136

    go.drugbank.com/drugs/DB11965
    Investigational

    SJG-136 has been used in trials studying the treatment of Recurrent Fallopian Tube Cancer, Secondary Acute Myeloid Leukemia, de Novo Myelodysplastic Syndromes, Recurrent Ovarian Epithelial Cancer, and Secondary Myelodysplastic Syndromes,...

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring
  3. Drug

    BMS-986094

    go.drugbank.com/drugs/DB11966
    Investigational

    INX-08189 has been used in trials studying the treatment of Hepatitis C, HCV (Genotype 1), and Hepatitis C Virus.

    Categories: Heterocyclic Compounds, 2-Ring
  4. Drug

    Binimetinib

    go.drugbank.com/drugs/DB11967
    ApprovedInvestigational

    Binimetinib, also known as _Mektovi_, is a potent and selective oral mitogen-activated protein kinase 1/2 (MEK 1/2) inhibitor which is combined with [Encorafenib].

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: MEKTOVI® 15 MG TABLETAS RECUBIERTAS
  5. Drug

    Uprosertib

    go.drugbank.com/drugs/DB11969
    Investigational

    Uprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical Cancer, and HER2/Neu Negative, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Vilaprisan

    go.drugbank.com/drugs/DB11971
    Investigational

    Vilaprisan has been used in trials studying the treatment of Leiomyoma and Clinical Trial, Phase I.

  7. Drug

    Golvatinib

    go.drugbank.com/drugs/DB11977
    Investigational

    Golvatinib has been investigated for the treatment of Platinum-Resistant Squamous Cell Carcinoma of the Head and Neck.

    Categories: Heterocyclic Compounds, 1-Ring, Vascular Endothelial Growth Factor Receptor-2, antagonists & inhibitors
  8. Drug

    Letaxaban

    go.drugbank.com/drugs/DB11984
    Investigational

    Letaxaban has been used in trials studying the treatment and prevention of Venous Thromboembolism and Acute Coronary Syndrome.

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Dapaconazole

    go.drugbank.com/drugs/DB11985
    Investigational

    Dapaconazole has been used in trials studying the treatment of Tinea Pedis.

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    GSK-2018682

    go.drugbank.com/drugs/DB11987
    Investigational

    GSK2018682 has been investigated for the treatment of Multiple Sclerosis, Relapsing-Remitting.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring