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SCH-486757
go.drugbank.com/drugs/DB12782InvestigationalSch 486757 has been used in trials studying the treatment of Cough.
Categories: Heterocyclic Compounds, 1-RingFuraprevir
go.drugbank.com/drugs/DB12785InvestigationalFuraprevir is under investigation in clinical trial NCT01523990 (A Study to Evaluate the Safety, Tolerability, and PK in Healthy Volunteers and HCV Genotype 1 Infected Patients).
Crotedumab
go.drugbank.com/drugs/DB12815InvestigationalCrotedumab has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
Lefamulin
go.drugbank.com/drugs/DB12825Approved[A183161] The chemical structure of lefamulin contains a tricyclic mutilin core that is necessary for some of its antimicrobial activity.[A183167] … A pleuromotilin is a more recently developed type of antibiotic that is derived from the fungus, Pleurotus mutilus.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesCebranopadol
go.drugbank.com/drugs/DB12830InvestigationalCebranopadol has been used in trials studying the treatment of Pain, Neoplasms, and Chronic Pain.
Categories: Heterocyclic Compounds, 2-RingOlipudase alfa
go.drugbank.com/drugs/DB12835ApprovedInvestigational[L42740] ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency in acid sphingomyelinase and the abnormal accumulation of the primary ASM substrate, sphingomyelin … [A251590] It was later approved by the European Commission on June 28, 2022 [L42740] and by the FDA on August 31, 2022.[L43145]
Pirnabine
go.drugbank.com/drugs/DB12840InvestigationalPirnabine has been used in trials studying the treatment of Chronic Idiopathic Constipation.
Categories: Guanylyl Cyclase C AgonistsPyroxamide
go.drugbank.com/drugs/DB12847InvestigationalPyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer, Precancerous Condition, and Myelodysplastic Syndromes, among others.
Categories: Heterocyclic Compounds, 1-RingPF-04217903
go.drugbank.com/drugs/DB12848InvestigationalPF-04217903 has been used in trials studying the treatment of Neoplasms.
Categories: Heterocyclic Compounds, 1-RingMiravirsen
go.drugbank.com/drugs/DB12851InvestigationalMiravirsen has been investigated for the treatment of Hepatitis C and Hepatitis C, Chronic.