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Gadoteric acid
go.drugbank.com/drugs/DB09132ApprovedInvestigational[A263141,A263106] Gadoterate is approved by the FDA under the brand name DOTAREM on 20th March 2013 for intravenous uses with magnetic resonance imaging (MRI) in the brain (intracranial), spine, and … due to a decreased tendency of gadolinium dechelation.
Voxelotor
go.drugbank.com/drugs/DB14975Approved[T734] Voxelotor was granted accelerated FDA approval on November 25 2019, as it is likely to be a promising treatment for the 100,000 individuals in the U.S. suffering from the disease, in addition … The EMA approved the use of voxelotor for the treatment of hemolytic anemia associated with sickle cell disease in February 2022.[L41419,L41424]
Prasugrel
go.drugbank.com/drugs/DB06209ApprovedInvestigationalR-138727 irreversibly binds to P2Y12 type ADP receptors on platelets thus preventing activation of the GPIIb/IIIa receptor complex. … Similar to clopidogrel, prasugrel is a prodrug that requires enzymatic transformation in the liver to its active metabolite, R-138727.
Categories: Purinergic P2Y Receptor AntagonistsPromazine
go.drugbank.com/drugs/DB00420ApprovedVet approvedWithdrawnIt is currently not approved for use in the United States. … A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Adrenergic alpha-1 Receptor AntagonistsPrazosin
go.drugbank.com/drugs/DB00457ApprovedInvestigational[L5828] It belongs to the class of drugs known as alpha-1 antagonists. … Prazosin is a drug used to treat hypertension. Prazosin is marketed by _Pfizer_ and was initially approved by the FDA in 1988.
Categories: Adrenergic alpha-1 Receptor AntagonistsProducts: CAPSULAS DE 1MGRilpivirine
go.drugbank.com/drugs/DB08864ApprovedInvestigational[A31329] The internal conformational flexibility of rilpivirine and the plasticity of it interacting binding site gives it a very high potency and reduces the chance of resistance compared to other NNRTI's … [L1030] On November 21, 2017, Rilpivirine, in combination with [dolutegravir], was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named
Categories: Antivirals used in combination for the treatment of HIV infectionsSynonyms: 4-{[4-({4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrileEtanercept
go.drugbank.com/drugs/DB00005ApprovedInvestigationalDimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. … [L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1.
Products: BENEPALI 50MG ILO I E FERAscorbyl phosphate
go.drugbank.com/drugs/DB11352ApprovedInvestigationalC that is readily absorbed into the skin with a hydrating effect on the skin [A27212]. … While ascorbyl phosphate salts provide a constant delivery of vitamin C into the skin, they also mediate an antioxidant action to act as a free radical scavenger and increases collagen production *in vitro
Mixtures: Le-Blen Vitamin C SerumEsterified estrogens
go.drugbank.com/drugs/DB09381ApprovedPreparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that the total is not <90%. … It is being also for the prevention and treatment of osteoporosis.
Corynebacterium diphtheriae
go.drugbank.com/drugs/DB09877ApprovedInvestigationalThe vaccine is intramuscularly administered to provide active immunization against diphtheria in infants and children. … *Corynebacterium diphtheriae* toxin is extracted from the pathogenic actinobacterium *C. diphtheriae* that causes diphtheria.
Mixtures: Td-pur für Erwachsene und Heranwachsende