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TGAAC94
go.drugbank.com/drugs/DB06175InvestigationalIt was under investigation in clinical trials to treat Inflammatory Arthritis. In 2007, one patient participating in the clinical trial died and the trial was placed on clinical hold by the FDA. … The Health Recombinant DNA Advisory Committee (RAC) concluded that a possible role of the gene transfer in this clinical course could not definitively be excluded due to the lack of data. [A264038]
Pirbuterol
go.drugbank.com/drugs/DB01291ApprovedWithdrawnenzyme which catalyzes the conversion of adenosine triphosphate (AlP) to cyclic-3† ,5†-adenosine monophosphate (c-AMP). … The pharmacologic effects of beta adrenergic agonist drugs, including pirbuterol, are at least in proof attributable to stimulation through beta adrenergic receptors of intracellular adenyl cyclase, the
Categories: Agents to Treat Airway DiseaseFluoride ion F-18
go.drugbank.com/drugs/DB09398ApprovedInvestigationalNo adverse reactions have been reported. … Sodium Fluoride F 18 Injection is a positron emitting radiopharmaceutical, no-carrier added.
Bromus secalinus pollen
go.drugbank.com/drugs/DB10836ApprovedBromus secalinus pollen is the pollen of the Bromus secalinus plant. Bromus secalinus pollen is mainly used in allergenic testing.
Mixtures: Mixture of Twenty-Two Standardized and Non-Standardized GrassesTypha latifolia pollen
go.drugbank.com/drugs/DB10860ApprovedTypha latifolia pollen is the pollen of the Typha latifolia plant. Typha latifolia pollen is mainly used in allergenic testing.
Mixtures: Mixture of Twenty-Two Standardized and Non-Standardized GrassesAplaviroc
go.drugbank.com/drugs/DB06497InvestigationalA spiro-diketo-piperazine; a potent noncompetitive allosteric antagonist of the CCR5 receptor with concomitantly potent antiviral effects for HIV-1.
Hyaluronidase (human recombinant)
go.drugbank.com/drugs/DB06205ApprovedInvestigational[A199026] Hyaluronidase has been used in surgical settings for at least the past 60 years to improve the diffusion of local anesthetics. … [A4033] Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents.
Phenylbutyric acid
go.drugbank.com/drugs/DB06819ApprovedInvestigational[A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders.[L386,L42105]
VX-148
go.drugbank.com/drugs/DB06103ExperimentalVX-148 is a second-generation, orally administered inhibitor of inosine monophosphate dehydrogenase (IMPDH). The IMPDH enzyme plays a key role in regulating immune response and proliferation of specific cell types, including lymphocytes....