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Displaying results 1881 - 1890 of 10000 in total
  1. Drug

    Cytarabine

    go.drugbank.com/drugs/DB00987
    ApprovedInvestigational

    A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. … Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle.

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone, 1-beta-D-Arabinofuranosylcytosine
  2. Drug

    Fenoterol

    go.drugbank.com/drugs/DB01288
    ApprovedWithdrawn

    Fenoterol is an adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.

    Synonyms: 1-(3,5-dihydroxyphenyl)-1-hydroxy-2-((4-hydroxyphenyl)isopropylamino)ethane, 5-{1-Hydroxy-2-[2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-benzene-1,3-diolInternational brands: Berotec N
  3. Drug

    Des(carbamimidoyl) zanamivir

    go.drugbank.com/drugs/DB03321
    Experimental

    Synonyms: 4-Amino-2-deoxy-2,3-dehydro-N-neuraminic acid, 4-AM-DANA
  4. Drug

    Recilisib

    go.drugbank.com/drugs/DB18310
    Experimental

    Synonyms: 4-((1e)-2-(((4-chlorophenyl)methyl)sulfonyl)ethenyl)benzoic acid, Benzoic acid, 4-((1e)-2-(((4-chlorophenyl)methyl)sulfonyl)ethenyl)-
  5. Drug

    Emtricitabine

    go.drugbank.com/drugs/DB00879
    ApprovedInvestigational

    Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 infection … [L9019] Emtricitabine was granted FDA approval on 2 July 2003.[L9019]

    Mixtures: TENOHOPE E (EMTRICITABINE 200 MG & TENOFOVIR DISOPROXIL FUMARATE 300 MG TABLETS), EMTRICITABINA E TENOFOVIR DISOPROXIL EGCategories: MATE 1 Substrates, Heterocyclic Compounds, 1-Ring
  6. Drug

    L-Octahydroindole-2-carboxylic acid

    go.drugbank.com/drugs/DB03409
    Experimental

    Synonyms: Perindopril impurity A, L-Octahydroindole-2-carboxylic acid
  7. Drug

    4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide

    go.drugbank.com/drugs/DB02565
    Experimental

    Synonyms: 4-dimethylamino-N-(6-hydroxycarbamoylhexyl)benzamide, N-hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide
  8. Drug

    Medroxyprogesterone acetate

    go.drugbank.com/drugs/DB00603
    ApprovedInvestigational

    Medroxyprogesterone acetate (MPA) is a [progesterone] derivative that is more resistant to metabolism for improved pharmacokinetic properties. … manage pain in endometriosis, prevent pregnancy, and is also used in palliative care for endometrial and renal carcinoma.

    Synonyms: (6α)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione, 6α-Methyl-4-pregnene-3,20-dion-17α-ol acetateMixtures: DIVICONT TABLETAS 1 MG/5 MG, DIVINA 2 MG + 2 MG /10 MG TABLET, 21 ADET
  9. Drug

    Resmetirom

    go.drugbank.com/drugs/DB12914
    ApprovedInvestigational

    Resmetirom is a thyroid hormone receptor-beta (THR-beta) agonist. … On March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic non-alcoholic steatohepatitis (NASH), which is a form of non-alcoholic fatty liver disease (NAFLD

    Synonyms: 1,2,4-Triazine-6-carbonitrile, 2-[3,5-dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-2,3,4,5-tetrahydro-3,5-dioxo-, 2-[3,5-Dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-2,3,4,5-tetrahydro-3,5-dioxo-1,2,4-triazine-6-carbonitrileCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  10. Drug

    VMD-928

    go.drugbank.com/drugs/DB18052
    Investigational

    Synonyms: 4-((4-AMINO-3-(4-CYCLOHEXYLPIPERAZIN-1-YL)-9,10-DIOXO-9,10-DIHYDROANTHRACEN-1-YL)AMINO)BENZOIC ACID, 4-{[4-Amino-3-(4-cyclohexylpiperazin-1-yl)-9,10-dioxo-9,10-dihydroanthracen-1-yl]amino}benzoic acid