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Methylprednisolone
go.drugbank.com/drugs/DB00959ApprovedInvestigationalVet approvedMethylprednisolone is a [prednisolone] derivative glucocorticoid with higher potency than [prednisone].[A188811] It was first described in the literature in the late 1950s.
Mixtures: Physicians EZ Use M-pred, Physicians EZ Use M-predCategories: Sex Hormones and Insulins, Cytochrome P-450 SubstratesProtionamide
go.drugbank.com/drugs/DB12667ApprovedInvestigationalWithdrawnProthionamide has been used in trials studying the treatment of MDR-TB and HIV Infections.
Categories: Heterocyclic Compounds, 1-RingProducts: TIONAMID 250 MG DRAJE, 500 ADET, TIONAMID 250 MG DRAJE, 50 ADETMethyldopa
go.drugbank.com/drugs/DB00968ApprovedInvestigational[A1499] Methyldopa exists in two isomers D-α-methyldopa and L-α-methyldopa, which is the active form. … Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent.
Mixtures: Supres 250 Tab, Aldoril 25 TabCategories: Adrenergic alpha-2 Receptor Agonists, Central alpha-2 Adrenergic AgonistMannitol
go.drugbank.com/drugs/DB00742ApprovedInvestigationalthis indication under the name BRONCHITOL® by Chiesi USA Inc. … As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure may be reduced.
Synonyms: D-Mannitol, D-(-)-MannitolInternational brands: Mannisol AGuaifenesin
go.drugbank.com/drugs/DB00874ApprovedInvestigationalVet approvedAfter the negotiation between FDA and major manufacturers, a voluntary transition of labels for not using guaifenesin in children under the age of 4 years was endorsed by FDA in 2008 [F4525]. … to be safe and effective in children under the age of 6 years [F4525].
Mixtures: BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML, SUDAFED EKSPEKTORAN 30 MG+100 MG/5 ML ŞURUP, 150 MLInternational brands: Duratuss GChlorpromazine
go.drugbank.com/drugs/DB00477ApprovedInvestigationalVet approvedLike the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine, 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amineEtanercept
go.drugbank.com/drugs/DB00005ApprovedInvestigationalEtanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids. … It is used to treat or manage a variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and juvenile idiopathic poly-articular arthritis (JIA).
Products: ENBREL ® 50 MG POLVO Y SOLVENTE PARA SOLUCION INYECTABLE, ENBREL 25 MG POLVO Y SOLVENTE PARA SOLUCIÓN INYECTABLE.Fentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approvedFentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. … [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose deaths).[L6748] Opioid overdoses kill an average of 11 Canadians daily.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide, N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamideBeclomethasone dipropionate
go.drugbank.com/drugs/DB00394ApprovedInvestigationalBeclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and later in a dry powder inhaler and an aqueous nasal spray. … Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone, which is structurally similar to [dexamethasone].
Synonyms: (11β,16β)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione, 9-chloro-11β-hydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dipropionateInternational brands: Clenil-AEthosuximide
go.drugbank.com/drugs/DB00593ApprovedInvestigationalAn anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 2-ethyl-2-methylsuccinimide, (±)-2-ethyl-2-methylsuccinimide