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Loteprednol etabonate
go.drugbank.com/drugs/DB14596ApprovedLoteprednol Etabonate (LE) is a topical corticoid anti-inflammatory. It is used in ophthalmic solution for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, sup...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Lotemax GelLenalidomide
go.drugbank.com/drugs/DB00480ApprovedInvestigationalLenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. It is a 4-amino-glutamyl analogue of thalidomide and like thalidomide, lenalidomi...
Categories: P-glycoprotein substratesProducts: Lenalidomid G.L. 5 mg Hartkapseln, Lenalidomid G.L. 10 mg HartkapselnDoxazosin
go.drugbank.com/drugs/DB00590ApprovedInvestigationalDoxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. Other members of this drug class include Prazosin, Terazosin, Tamsulosin, and Alfuzosin. Because of its long-lasti...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: CARDULAR PP 4MG, CARDULAR PP 8MGDigoxin
go.drugbank.com/drugs/DB00390ApprovedInvestigationalDigoxin is one of the oldest cardiovascular medications used today. It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. Digoxin is classified as a cardiac glycoside and was initially approved by the...
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: LANOXIN PG 62.5MCG TABLETS, LANOXIN-PG PAEDIATRIC/GERIATRIC TABLET 0.0625 mgLacosamide
go.drugbank.com/drugs/DB06218ApprovedInvestigationalLacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of intera...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: LACOSAMIDE G.L., Lacasa 50 Lacosamide Film Coated Tablets Ph. Eur. 50 mgCetrimonium
go.drugbank.com/drugs/DB01718ApprovedCetrimonium is a quaternary ammonium cation whose salts are used as antiseptics.
Mixtures: VIDISIC GEL, Xylonor GelProducts: SOOV BITE GELApremilast
go.drugbank.com/drugs/DB05676ApprovedInvestigationalApremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases. It belongs to the same drug class as Roflumilast and Crisaborole...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Apremilast G.L. 30 mg-FilmtablettenVenlafaxine
go.drugbank.com/drugs/DB00285ApprovedInvestigationalVenlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Venlafaxin G.L. 75 mg - Tabletten, Venlafaxin G.L. 25 mg - TablettenGanciclovir
go.drugbank.com/drugs/DB01004ApprovedInvestigationalAn acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Products: VIRGAN EYE GEL 1.5 mg/g, VIRGAN® GEL OFTALMICOBromazepam
go.drugbank.com/drugs/DB01558ApprovedIllicitOne of the benzodiazepines that is used in the treatment of anxiety disorders. It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances. It is a intermediate-acting benzodiazepine.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: BROMAZEPAM N&P, Bromazepam G.L. 3 mg - Filmtabletten