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Diacerein
go.drugbank.com/drugs/DB11994ApprovedInvestigationalWithdrawnDiacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including severe diarrhea . Diacerein is und...
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsDitiocarb zinc
go.drugbank.com/drugs/DB14193ApprovedDitiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and zinc. It also a dermatological sensitizer and allergen. Sensitivity to ditiocarb zinc may be identified with a clinical patch test.
Categories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP2E1 InhibitorsHydrocortisone aceponate
go.drugbank.com/drugs/DB14538InvestigationalVet approvedCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InducersCurcumin sulfate
go.drugbank.com/drugs/DB14635ExperimentalCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2B6 InhibitorsPrednisone acetate
go.drugbank.com/drugs/DB14646ApprovedInvestigationalWithdrawnCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersClocortolone acetate
go.drugbank.com/drugs/DB14652ExperimentalCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersNorethindrone enanthate
go.drugbank.com/drugs/DB14678InvestigationalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDextrorphan
go.drugbank.com/drugs/DB14682ExperimentalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesTrastuzumab deruxtecan
go.drugbank.com/drugs/DB14962ApprovedInvestigationalTrastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for use in certain types of treatment-resistant HER2-positive cancers. It is classified as an antibody-drug conjugate. The cleavabl...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesCrizotinib
go.drugbank.com/drugs/DB08865ApprovedInvestigationalCrizotinib is a tyrosine kinase receptor inhibitor used for the treatment of anaplastic lymphoma kinase (ALK) or ROS1-positive non-small cell lung cancer (NSCLC) tumors, as well as ALK-positive anaplastic large cell lymphoma (ALCL) and i...
Categories: P-glycoprotein inhibitors, P-glycoprotein substrates