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No approved therapeutic indications.
- Mechanism
- Curator reviewed · 2 references
Curcumin acts as a scavenger of oxygen species, such as hydroxyl radical, superoxide anion, and singlet oxygen and inhibit lipid peroxidation as well as peroxide-induced DNA damage. Curcumin mediates potent anti-inflammatory agent and anti-carcinogenic actions via modulating various signalling molecules. It suppresses a number of key elements in cellular signal transduction pathways pertinent to growth, differentiation, and malignant transformation; it was demonstrated in vitro that curcumin inhibits protein kinases, c-Jun/AP-1 activation, prostaglandin biosynthesis, and the activity and expression of the enzyme cyclooxygenase (COX)-2.
- Primary indication
- No approved therapeutic indications.Curator reviewed
- Formula / weight
- C21H20O9S · 448.44 g/mol (avg)
- Also known as
- Curcumin monosulfate · Curcumin sulphate
Resolves to
NEJVQQBBTRFOHB-FCXRPNKRSA-NSMILESCOC1=CC(\C=C\C(=O)CC(=O)\C=C\C2=CC=C(OS(O)(=O)=O)C(OC)=C2)=CC=C1OWhat you can answer from here — as of April 02, 2025
Which drugs share a target with Curcumin sulfate, and which of those have an active Phase 3 trial?