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Displaying results 1891 - 1900 of 10000 in total
  1. Drug

    Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate

    go.drugbank.com/drugs/DB14701
    Experimental

    Synonyms: Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate, 5-Quinolinepropanoic acid, 8-hydroxy-alpha-(2-propyn-1-ylamino)-, ethyl ester
  2. Drug

    1,3-Bis((1-methylethyl)amino)propan-2-ol

    go.drugbank.com/drugs/DB16631
    Investigational

  3. Drug

    Minocycline

    go.drugbank.com/drugs/DB01017
    ApprovedInvestigational

    [A190723] Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. … [A190681] It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria.

    Synonyms: (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, 7-Dimethylamino-6-demethyl-6-deoxytetracyclineProducts: PERIOCLINE PERIODONTAL OINTMENT 2% W/W, XELTETRA-M
  4. Drug

    Alosetron

    go.drugbank.com/drugs/DB00969
    ApprovedWithdrawn

    Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. … Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes.

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one
  5. Drug

    Sulfatide

    go.drugbank.com/drugs/DB04780
    Experimental

    Any of a class of cerebroside sulfuric esters, they are found largely in the medullated nerve fibers and may accumulate in metachromatic leukodystrophy.

    Synonyms: 2-hydroxytetracosanoyl sulfatide, 2-hydroxytetracosanoylgalactosylceramide sulfate
  6. Drug

    Telaprevir

    go.drugbank.com/drugs/DB05521
    ApprovedWithdrawn

    Telaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). … Telaprevir is an inhibitor of NS3/4A, a serine protease enzyme, encoded by HCV genotype 1 [FDA Label].

    Synonyms: (1S,3aR,6aS)-(2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-((1S)-1-((cyclopropylamino)oxoacetyl)butyl)octahydrocyclopenta(c)pyrrole-1-carboxamideCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  7. Drug

    Dactinomycin

    go.drugbank.com/drugs/DB00970
    ApprovedInvestigational

    A compound composed of a two cyclic peptides attached to a phenoxazine that is derived from streptomyces parvullus. … As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)

    Synonyms: N,N'-((2-AMINO-4,6-DIMETHYL-3-OXO-3H-PHENOXAZINE-1,9-DIYL)-BIS(CARBONYLIMINO(2-HYDROXYPROPYLIDENE)CARBONYLIMINOISOBUTYLIDENECARBONYL-1,2-PYRROLIDINEDIYLCARBONYL(METHYLIMINO)METHYLENECARBONYL))BIS(N-METHYL-L-VALINE, 2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-i)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamideCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitors
  8. Drug

    Pyridoxal phosphate

    go.drugbank.com/drugs/DB00114
    ApprovedInvestigationalNutraceutical

    This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.

    Mixtures: Xyzbac G, L-Methyl-B6-B12Categories: Vitamin B Complex, Heterocyclic Compounds, 1-Ring
  9. Drug

    Chloramphenicol

    go.drugbank.com/drugs/DB00446
    ApprovedInvestigationalVet approvedWithdrawn

    It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic.

    Synonyms: D-(−)-threo-1-p-nitrophenyl-2-dichloroacetylamino-1,3-propanediol, D-(−)-2,2-dichloro-N-(β-hydroxy-α-(hydroxymethyl)-p-nitrophenylethyl)acetamideMixtures: CORTIFENOL H POMADA OFTALMICA 4 G, CLOXONA-O
  10. Drug

    Histidine

    go.drugbank.com/drugs/DB00117
    ApprovedInvestigationalNutraceutical

    An essential amino acid that is required for the production of histamine.

    Synonyms: (S)-4-(2-Amino-2-carboxyethyl)imidazole, (S)-a-Amino-1H-imidazole-4-propanoic acidMixtures: AMINOMIX 2 NOVUM 1000 ML, AMINOMIX 2 NOVUM 1500 ML