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mRNA-1283
go.drugbank.com/drugs/DB22668ApprovedInvestigationalmRNA-1283 is a nucleoside-modified messenger RNA (mRNA) encoding the N-terminal domain (NTD) and receptor-binding domain (RBD) of the spike glycoprotein of the SARS-CoV-2 Omicron variant lineage JN.1. … [L53408] As opposed to previously approved COVID-19 mRNA vaccines, including the original [Moderna COVID-19 Vaccine], mRNA-1283 encodes only the immunodominant regions (NTD and RBD) of the SARS-CoV-
Levodopa
go.drugbank.com/drugs/DB01235ApprovedInvestigationalLevodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label]. … The first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product called Sinemet that was approved on May 2, 1975[A177781,L6133].
Mixtures: Pentiro 150 mg/37,5 mg/200 mg Filmtabletten, Sastravi 150 mg/37,5 mg/200 mg FilmtablettenCX-052075
go.drugbank.com/drugs/DB31655Approvedthe SARS-CoV-2 spike protein, allowing for a more targeted immune response and the use of a significantly smaller amount of mRNA per dose. … CX-052075 is a nucleoside-modified messenger RNA (mRNA) encoding the N-terminal domain (NTD) and receptor-binding domain (RBD) of the spike glycoprotein of the SARS-CoV-2 Omicron variant sublineage LP.8.1
Promazine
go.drugbank.com/drugs/DB00420ApprovedVet approvedWithdrawnA phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic.
Categories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 SubstratesSynonyms: 10-(3-(Dimethylamino)propyl)phenothiazine, N,N-dimethyl-3-(10H-phenothiazin-10-yl)-propan-1-amineMomelotinib
go.drugbank.com/drugs/DB11763ApprovedInvestigational[A261566] First approved by the FDA on September 15, 2023,[L48206] momelotinib is used to treat myelofibrosis. … Momelotinib is a Janus Kinase 1 (JAK1) and 2 (JAK2) inhibitor. It is a competitive inhibitor of JAK ATP binding.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates(1r)-4-[(1e,3e,5e,7z,9e,11z,13e,15e)-17-Hydroxy-3,7,12,16-Tetramethylheptadeca-1,3,5,7,9,11,13,15-Octaen-1-Yl]-3,5,5-Trimethylcyclohex-3-En-1-Ol
go.drugbank.com/drugs/DB02253ExperimentalSynonyms: (1r)-4-[(1e,3e,5e,7z,9e,11z,13e,15e)-17-Hydroxy-3,7,12,16-Tetramethylheptadeca-1,3,5,7,9,11,13,15-Octaen-1-Yl]-3,5,5-Trimethylcyclohex-3-En-1-OlRiltozinameran
go.drugbank.com/drugs/DB17095ApprovedInvestigationalThe Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021. … [L43917] Riltozinameran is an mRNA vaccine encoding the S glycoprotein of SARS-CoV-2 Omicron variant lineage BA.1.
Desoximetasone
go.drugbank.com/drugs/DB00547ApprovedA topical anti-inflammatory glucocorticoid used in dermatoses, skin allergies, psoriasis, etc.
Products: ANTOX® 500 MG, Topicort Crm 2.5mg/gmAluminum zirconium octachlorohydrex gly
go.drugbank.com/drugs/DB11200ApprovedIt is an active antiperspirant agent [L2705], [L2706]. It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores.
Products: Dior Homme Sans Alcohol Free Antiperspirant, Dr. NonaLoteprednol etabonate
go.drugbank.com/drugs/DB14596ApprovedAs a nasal spray, it can be used for the treatment and management of seasonal allergic rhinitis. … Loteprednol Etabonate (LE) is a topical corticoid anti-inflammatory.
Mixtures: TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET, ZYLET OFTALMIK SUSPANSIYON, 2.5 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates