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Displaying results 1931 - 1940 of 10000 in total

Drug
Ivermectin
go.drugbank.com/drugs/DB00602
ApprovedInvestigationalVet approved
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of _Streptomyces avermitilis … [L31453] Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A<sub>1a</sub> (22,23-dihydroavermectin B<sub>1a</sub>) and 10% 5-O-demethyl-25-de
Categories: Compounds used in a research, industrial, or household setting
Drug
Carbinoxamine
go.drugbank.com/drugs/DB00748
Approved
Carbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. … This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding.
Drug
Desipramine
go.drugbank.com/drugs/DB01151
Approved
See toxicity section below for a complete listing of side effects. … Secondary amine TCAs, such as desipramine and nortriptyline, are more potent inhibitors of norepinephrine reuptake than tertiary amine TCAs, such as amitriptyline and doxepine.
Categories: Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index, Serotonin Receptor Antagonists
Drug
Nesiritide
go.drugbank.com/drugs/DB04899
ApprovedInvestigationalWithdrawn
Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). … Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.
Drug
Enflurane
go.drugbank.com/drugs/DB00228
ApprovedVet approvedWithdrawn
Enflurane is a halogenated inhalational anesthetic initially approved by the FDA in 1972. Since this date, it has been withdrawn from the US market.
Drug
Manganese gluconate
go.drugbank.com/drugs/DB11141
Approved
Manganese gluconate is a direct ingredient in food substances as a nutrient supplement. In pharmaceutical preparations it is used as a [DB06757] supplement. … Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O.
Mixtures: Vitamin E 400 Iu With Selenium, Vitamin C & Manganese
Drug
BNT162B2 Omicron (LP.8.1)
go.drugbank.com/drugs/DB23337
Approved
BNT162B2 Omicron (LP.8.1) is the active ingredient in the 2025-2026 formulation of Pfizer and BioNTech's Comirnaty mRNA vaccine for COVID-19. It encodes the spike protein from the Omicron LP.8.1 subvariant of SARS-CoV-2. The 2025-2026 fo...
Drug
Icodextrin
go.drugbank.com/drugs/DB00702
ApprovedInvestigational
It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport via peritoneal lymphatic pathways. … Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers.
Mixtures: EXTRANEAL CON ICODEXTRIN AL 7.5%Categories: Compounds used in a research, industrial, or household setting
Drug
Uridine triacetate
go.drugbank.com/drugs/DB09144
Approved
As a result, these metabolites are associated with various unpleasant side effects such as neutropenia, mucositis, diarrhea, and hand–foot syndrome. … As a result of UMPS deficiency, patients experience a systemic deficiency of pyrimidine nucleotides, accounting for most symptoms of the disease.
Drug
Dexamethasone
go.drugbank.com/drugs/DB01234
ApprovedInvestigationalVet approved
Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic … [L10695] In a press release for the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial on 16 June 2020, dexamethasone was recommended for use in COVID-19 patients with severe respiratory symptoms
Mixtures: AK-Trol, LERGOSIN-ACategories: Corticosteroid Hormone Receptor Agonists