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Exagamglogene autotemcel
go.drugbank.com/drugs/DB15572ApprovedInvestigationalSickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage...
Synonyms: Autologous CD34+ cells isolated from mobilised peripheral blood by positive selection, modified by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) mediatedMesenchymal stem cell-derived exosomes
go.drugbank.com/drugs/DB24445InvestigationalMesenchymal Stem Cell-Derived Exosomes is a biologic drug. Mesenchymal Stem Cell-Derived Exosomes is under investigation in clinical trial NCT07183384 (MSC Exosome Therapy for Post-Preeclampsia Endothelial Dysfunction).
Synonyms: exosomes derived from mesenchymal stem cellsChitin
go.drugbank.com/drugs/DB15142InvestigationalShrimp shell chitin is under investigation in clinical trial NCT00863356 (Trial of a Novel Chitosan Hemostatic Sealant in the Management of Complicated Epistaxis).
Synonyms: CHITIN FROM CRAB SHELLS, CHITIN FROM SHRIMP SHELLSVirulizin
go.drugbank.com/drugs/DB17098InvestigationalSynonyms: Immunomodulator extracted from bovine bile, Macrophage activator extracted from bovine bileAllogeneic natural killer cells
go.drugbank.com/drugs/DB18630InvestigationalSynonyms: Allogeneic ex vivo-generated natural killer cells from CD34+ umbilical cord blood progenitor cellsINM005
go.drugbank.com/drugs/DB16499InvestigationalINM005 was under investigation in clinical trials for the treatment of COVID-19. It was studied for pharmacokinetics, efficacy, and safety in a completed trial (NCT04494984). Additionally, a retrospective cohort study investigated the ef...
Synonyms: INM-005 (PURIFIED FAB'2 FRACTION OF EQUINE HYPERIMMUNE SERUM GENERATED FROM ANTIGENIC STIMULATION WITH THE SARS-COV2 RBD PROTEIN)Nalotimagene carmaleucel
go.drugbank.com/drugs/DB19155InvestigationalSynonyms: Cells are derived from the haematopoietic stem cell (HSC) donor and are genetically modified ex vivo with a non-replicative SFCMM-3 gamma- retroviral vector derived from MoGTA002
go.drugbank.com/drugs/DB17187InvestigationalSynonyms: Allogeneic ex-vivo generated CD56+CD3-natural killer cells from CD34+ umbilical cord blood progenitor cells, Allogeneic UCB-NK cellsYeast beta-D-glucan
go.drugbank.com/drugs/DB19271InvestigationalYeast beta-D-glucan is under investigation in clinical trial NCT00632008 (Soluble Beta-glucan (SBG) as Treatment for Diabetic Foot Ulcers).
Synonyms: -glucan from saccharomyces cerevisiae, Microparticulate beta-(1,3)(1,6) glucan from saccharomyces cerevisiae