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Displaying results 11 - 20 of 9220 in total
  1. Drug

    Obexelimab

    go.drugbank.com/drugs/DB15032
    Investigational

    Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).

    Synonyms: XMAB5871 (HUMANIZED ANTI-CD19 ANTIBODY WITH AN FC PORTION ENGINEERED FOR INCREASED AFFINITY (200- TO 400-FOLD OVER NATIVE IGG) TO FCGRIIB), humanized anti-CD19, Fc engineered, monoclonal antibody with enhanced binding to FcyRIIb
  2. Drug

    Pivekimab sunirine

    go.drugbank.com/drugs/DB17337
    ApprovedInvestigational

    Synonyms: Indolino-benzodiazepine compound (sulfonated DGN549-C) conjugated to the humanized anti-CD123 monoclonal antibody (G4723A)
  3. Drug

    AVR-RD-05

    go.drugbank.com/drugs/DB18631
    Experimental

    It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).

    Synonyms: Ex vivo, lentiviral vector (LV)-mediated, genetically modified autologous cell therapy intended for the stable provision of functional human iduronate-2-sulfatase (IDS) enzyme to subjects with Hunter syndrome
  4. Drug

    AGRO100

    go.drugbank.com/drugs/DB04998
    Investigational

    AGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells. … Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor cell.

    Synonyms: Nucleic acid aptamer binding to tumor cell nucleon
  5. Drug

    ALT-P1

    go.drugbank.com/drugs/DB18485
    Investigational

    ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.

    Synonyms: Recombinant human growth hormone fused to alpha1-antitrypsin variant
  6. Drug

    Ozuriftamab vedotin

    go.drugbank.com/drugs/DB17422
    Investigational

    Synonyms: Ba-302 conjugated to monomethyl auristatin e
  7. Drug

    ANX-005

    go.drugbank.com/drugs/DB16977
    Investigational

    Synonyms: Humanized Igg4 Monoclonal Antibody Binding To Human C1Q
  8. Drug

    MM-111

    go.drugbank.com/drugs/DB17983
    Investigational

    MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.

    Synonyms: Antibody bispecific for erbb2 and erbb3
  9. Drug

    Mubodina

    go.drugbank.com/drugs/DB17616
    Experimental

    Mubodina is an investigational drug developed by Adienne Pharma & Biotech. It is a recombinant human minibody directed against complement component C5.

    Synonyms: Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1
  10. Drug

    STM-217

    go.drugbank.com/drugs/DB17358
    Experimental

    Synonyms: Soluble receptor fused to part of an antibody that is designed to block the growth factor activin a