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Displaying results 11 - 20 of 7399 in total
  1. Drug

    Lerodalcibep

    go.drugbank.com/drugs/DB19071
    ApprovedInvestigational

    [A275273] Lerodalcibep prevents the actions of PCSK9 and allows more LDL to bind to LDLR and be cleared from circulation. … [L54738] Approved by the FDA on December 15, 2025, lerodalcibep is indicated as an adjunct to diet and exercise to reduce low-density lipoprotein cholesterol (LDL-C) in adults with hypercholesterolemia

    Synonyms: Engineered binding protein (1-96) anti-(human proprotein convertase subtilisin/kexin type 9), derived from human tenth fibronectin type iii domain, fused via peptidyl linker (97gsgsgs102) to human serum
  2. Drug

    Unexpanded umbilical cord-derived allogeneic CD34- hematopoietic stem cells

    go.drugbank.com/drugs/DB28348
    Approved

    [L54106] Zemcelpro also contains [dorocubicel], a preparation CD34+ HSCs derived from the same cord blood sample and expanded _ex vivo_ using [UM-171].

    Synonyms: Unexpanded CD34- cells from which the CD3+ cells are the active fraction
  3. Drug

    DT-DEC01

    go.drugbank.com/drugs/DB19433
    Experimental

    DT-DEC01 is a novel Dystrophin Expressing Chimeric (DEC) cell therapy being investigated by Dystrogen Therapeutics Corporation.

    Synonyms: Dystrophin Expressing Chimeric Cells derived from allogenic normal human myoblast and autologous DMD myoblast from Duchenne muscular dystrophy affected donor
  4. Drug

    Pivekimab sunirine

    go.drugbank.com/drugs/DB17337
    ApprovedInvestigational

    Synonyms: Indolino-benzodiazepine compound (sulfonated DGN549-C) conjugated to the humanized anti-CD123 monoclonal antibody (G4723A)
  5. Drug

    AGRO100

    go.drugbank.com/drugs/DB04998
    Investigational

    AGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells. … Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor cell.

    Synonyms: Nucleic acid aptamer binding to tumor cell nucleon
  6. Drug

    Autologous adipose-derived stromal vascular fraction cells

    go.drugbank.com/drugs/DB18679
    Investigational

    Synonyms: Autologous stromal vascular fraction from adipose tissue, Autologous stromal vascular cell fraction from adipose tissue
  7. Drug

    Expanded human allogeneic neural retinal progenitor cells extracted from neural retina

    go.drugbank.com/drugs/DB17913
    Experimental

    Synonyms: Expanded human allogeneic neural retinal progenitor cells extracted from neural retina
  8. Drug

    ALT-P1

    go.drugbank.com/drugs/DB18485
    Investigational

    ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.

    Synonyms: Recombinant human growth hormone fused to alpha1-antitrypsin variant
  9. Drug

    Silk sericin

    go.drugbank.com/drugs/DB15531
    Investigational

    Synonyms: Sericin (from silkworm)
  10. Drug

    Ozuriftamab vedotin

    go.drugbank.com/drugs/DB17422
    Investigational

    Synonyms: Ba-302 conjugated to monomethyl auristatin e