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Displaying results 11 - 20 of 105 in total
  1. Drug

    Teprotumumab

    go.drugbank.com/drugs/DB06343
    ApprovedInvestigational

    Teprotumumab is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor.

    Categories: Insulin-like Growth Factor-1 Receptor InhibitorSynonyms: Immunoglobulin G1, anti-(human insulin-like growth factor I receptor) (human monoclonal heavy chain), disulfide with human monoclonal light chain, dimer
  2. Drug

    Recombinant human insulin-like growth factor 1

    go.drugbank.com/drugs/DB18684
    Experimental

    Synonyms: Recombinant human insulin-like growth factor 1
  3. Drug

    Veligrotug

    go.drugbank.com/drugs/DB18976
    ApprovedInvestigational

    Veligrotug is a humanized IgG1 monoclonal antibody that binds the insulin-like growth factor-1 receptor and blocks ligand-induced receptor autophosphorylation, interrupting IGF-1R signaling.

    Categories: Insulin-like Growth Factor-1 Receptor InhibitorSynonyms: Immunoglobulin G1, anti-(human insulin-like growth factor I receptor) (human-Mus musculus monoclonal VRDN-001 γ1-chain), disulfide with human-Mus musculus monoclonal VRDN-001 κ-chain, dimer, Immunoglobulin G1-kappa, anti-[Homo sapiens IGF1R (insulin-like growth factor 1 receptor, IGF1-R, IGF-1R, CD221)], chimeric monoclonal antibody (gamma1 heavy chain chimeric (1-454) [VH (Mus musculus IGHV1S81
  4. Drug

    Insulin-like growth factor II

    go.drugbank.com/drugs/DB14472
    Investigational

    This factor presents effects related to growth regulation, insulin-like and mitogenic activities. … The insulin-like growth factor II is a well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood.

    Categories: Insulin-like growth factorSynonyms: Human insulin-like growth factor II, Insulin-like growth factor II (human)
  5. Drug

    Proinsulin human

    go.drugbank.com/drugs/DB17875
    Investigational

    Categories: InsulinSynonyms: Proinsulin human, Proinsulin biosynthetic human
  6. Drug

    Tralesinidase alfa

    go.drugbank.com/drugs/DB17657
    Investigational

    Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2.

    Categories: Insulin-like growth factorSynonyms: Recombinant human NAGLU-insulin-like growth factor II, Recombinant human alpha-N-acetylglucosaminidase-insulin-like growth factor-2
  7. Drug

    C-peptide

    go.drugbank.com/drugs/DB16187
    Investigational

    C-peptide is under investigation in clinical trial NCT00278980 (Effect of C-peptide on Diabetic Peripheral Neuropathy).

    Synonyms: Insulin c-peptide, Human c-peptideCategories: Insulin
  8. Drug

    Somatotropin

    go.drugbank.com/drugs/DB00052
    ApprovedInvestigational

    Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. … It has an identical primary protein structure to endogenous human growth hormone.[A228188] Recombinant HGH has been commercially available since 1985 after its development by Genentech.

    Categories: Sex Hormones and Insulins, Recombinant Human Growth HormoneSynonyms: Human growth hormone, Somatotropin human
  9. Drug

    AGT-182

    go.drugbank.com/drugs/DB17630
    Investigational

    AGT-182 is an investigational enzyme replacement therapy engineered by the fusion of the iduronate-2-sulfatase (IDS) enzyme and a human insulin receptor monoclonal antibody.

    Synonyms: Recombinant human insulin receptor monoclonal antibody-fused iduronate 2-sulfatase
  10. Drug

    Somatrogon

    go.drugbank.com/drugs/DB14960
    ApprovedInvestigational

    C-terminus of human growth hormone. … Somatrogon is a long-acting recombinant human growth hormone.

    Categories: Sex Hormones and Insulins, Recombinant Human Growth HormoneSynonyms: 118-145-GONADOTROPIN, CHORIONIC (HUMAN .BETA.-SUBUNIT) FUSION PROTEIN WITH SOMATOTROPIN (HUMAN) FUSION PROTEIN WITH 118-145-CHORIONIC GONADOTROPIN (HUMAN .BETA., HUMAN GROWTH HORMONE-CARBOXY-TERMINAL PEPTIDE (CTP) OF THE BETA CHAIN OF HUMAN CHORIONIC GONADOTROPIN FUSION PROTEIN