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Displaying results 191 - 200 of 10000 in total
  1. Drug

    Inupadenant

    go.drugbank.com/drugs/DB19129
    Investigational

    Inupadenant is under investigation in clinical trial NCT05060432 (Study of EOS-448 With Standard of Care And/or Investigational Therapies in Participants With Advanced Solid Tumors).

    Synonyms: (+)-5-amino-3-(2-(4-(2,4-difluoro-5-(2-((s)-methanesulfinyl)ethoxy)phenyl)piperazin-1- yl)ethyl)-8-(furan-2-yl)thiazolo(5,4-e)(1,2,4)triazolo(1,5-c)pyrimidin-2(3h)-one, Thiazolo(5,4-e)(1,2,4)triazolo(1,5-c)pyrimidin-2(3h)-one, 5-amino-3-(2-(4-(2,4-difluoro-5-(2-((s)-methylsulfinyl)ethoxy)phenyl)-1-piperazinyl)ethyl)-8-(2-furanyl)-
  2. Drug

    Lumiliximab

    go.drugbank.com/drugs/DB06162
    Investigational

    Lumiliximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug. … Clinical trials for CLL were terminated in 2010, and for allergic asthma in 2007. Results published from the CLL clinical trial failed to meet primary endpoints.

    Synonyms: IMMUNOGLOBULIN G1, ANTI-(HUMAN IMMUNOGLOBULIN E RECEPTOR TYPE II) (HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .KAPPA.-CHAIN, DIMER, IMMUNOGLOBULIN G1, ANTI-(HUMAN IMMUNOGLOBULIN E RECEPTOR TYPE II) (HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .GAMMA.1-CHAIN), DISULPHIDE WITH HUMAN-MACACA IRUS MONOCLONAL IDEC-152 .KAPPA.-CHAIN, DIMER
  3. Drug

    NM-004

    go.drugbank.com/drugs/DB18066
    Experimental

    Synonyms: 5-((e)-(4-(carboxymethyl)phenyl)azo)-2-hydroxy-benzoic acid, Benzeneacetic acid, 4-(2-(3-carboxy-4-hydroxyphenyl)diazenyl)-
  4. Drug

    Canoctakin

    go.drugbank.com/drugs/DB18195
    Investigational

    Synonyms: Recombinant dna derived, human interleukin 8 (cxcl8) mutein, produced in escherichia coli: (44,48,97,98-tetra-l-lysine)human interleukin 8 precursor-(34-99)- peptide anti-inflammatory, Interleukin 8 (synthetic human clone dncxcl8 increased-glycosaminoglycan binding isoform pa401)
  5. Drug

    Suratadenoturev

    go.drugbank.com/drugs/DB18672
    Investigational

    Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.

    Synonyms: A recombinant replication-competent adenovirus type 5 (Ad-5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and replaced by an expression cassette containing, A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human telomerase reverse transcriptase (hTERT) and IRES, respectively.
  6. Drug

    Demplatin pegraglumer

    go.drugbank.com/drugs/DB14807
    Investigational

    Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).

    Synonyms: A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl linkagecisplatin is incorporated in polymeric micelles via polymer-metal complex formation with
  7. Drug

    SEL120-34A free base

    go.drugbank.com/drugs/DB18107
    Investigational

    Synonyms: Cdk8-in-2 free base, 4h-imidazo(4,5,1-ij)quinoline, 7,8-dibromo-5,6-dihydro-9-methyl-2-(1-piperazinyl)-
  8. Drug

    Pudexacianinium

    go.drugbank.com/drugs/DB19161
    Investigational

    Pudexacianinium is under investigation in clinical trial NCT05754333 (A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery).

    Synonyms: )-1,1-dimethyl-1h-benz(e)indolium ion, Pudexacianinium ion
  9. Drug

    Crotonaldehyde

    go.drugbank.com/drugs/DB04381
    Experimental

    Synonyms: (E)-crotonaldehyde, 2-Butenal
  10. Drug

    Icosapent ethyl

    go.drugbank.com/drugs/DB08887
    ApprovedInvestigationalNutraceutical

    Icosapent ethyl or ethyl eicosapentaenoic acid is a synthetic derivative of the omega-3 fatty acid eicosapentaenoic acid (EPA). … It is used as an adjunct therapy for severe hypertriglyceridemia (TG levels > 500 mg/dL) and to reduce the risk of cardiovascular events in certain patients with elevated triglycerides.

    Categories: Fatty Acids, Omega-3Synonyms: E-EPA, (all-Z)-5,8,11,14,17-Eicosapentaenoic acid ethyl ester