Search

Displaying results 1991 - 2000 of 10000 in total
  1. Drug

    Ramipril

    go.drugbank.com/drugs/DB00178
    ApprovedInvestigational

    Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. … Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).

    Synonyms: (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acidMixtures: Coreyra 10 mg/5 mg Hartkapseln, Ramipril/Amlodipin/HCT 1A Pharma 10 mg/5 mg/25 mg – Hartkapseln
  2. Drug

    Autologous ex vivo expanded cd4+-enriched leukocytes treated with the de-methylating agent 5-aza-deoxycytidine

    go.drugbank.com/drugs/DB19219
    Investigational

    Synonyms: Autologous ex vivo expanded cd4+-enriched leukocytes treated with the de-methylating agent 5-aza-deoxycytidine
  3. Drug

    Sodium bicarbonate

    go.drugbank.com/drugs/DB01390
    ApprovedInvestigational

    Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

    Mixtures: PRONAT 500 mg+267 mg+160 mg/10 ml ORAL SÜSPANSIYON, 200 ML, GASVİN 500 MG + 267 MG + 160 MG / 10 ML SÜSPANSİYON, 200 MLProducts: NURSE BABY 50 MG/5 ML ORAL ÇÖZELTİ, 10 ADET, Sodium Bicarbonate 5 gr (325 mg)
  4. Drug

    Gunagratinib

    go.drugbank.com/drugs/DB18191
    Experimental

    Synonyms: (s)-1-(1-acryloylpyrrolidin-3-yl)-3-((3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1h-pyrazole-4-carboxamide, 1h-pyrazole-4-carboxamide, 3-(2-(3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1-((3s)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl)-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    Repotrectinib

    go.drugbank.com/drugs/DB16826
    ApprovedInvestigational

    [A262056] ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ROS1 G2032R is responsible for 50 to 60% of [crizotinib]-resistant cases. … This approval is based on favorable results from the TRIDENT-1 study, where the objective response rate was 79% in TKI-naive patients and 38% in TKI-pretreated patients respectively.[L48741]

    Synonyms: (3R,6S,)-45-FLUORO-3,6-DIMETHYL-5-OXA-2,8-DIAZA-1(5,3)-PYRAZOLO(1,5-A)PYRIMIDINA-4(1,2)-BENZENANONAPHAN-9-ONE, 1,15-ETHENO-1H-PYRAZOLO(4,3-F)(1,4,8,10)BENZOXATRIAZACYCLOTRIDECIN-4(5H)-ONE, 11-FLUORO-6,7,13,14-TETRAHYDRO-7,13-DIMETHYL-, (7S,13R)-Categories: Heterocyclic Compounds, 1-Ring, MATE 2 Inhibitors
  6. Drug

    Rocuronium

    go.drugbank.com/drugs/DB00728
    ApprovedInvestigational

    [Sugammadex] is a γ-cyclodextrin derivative that has been introduced as a novel agent to reverse the action of rocuronium. … Rocuronium (rapid onset-curonium) is a desacetoxy analogue of vecuronium with a more rapid onset of action.

    Products: JECRON 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ ,10 FLAKON, ANTARİN 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 10 ADET
  7. Drug

    MMDA

    go.drugbank.com/drugs/DB01442
    ExperimentalIllicit

    MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen.

    Synonyms: 5-Methoxy-3,4-methylenedioxyamphetamine, 3-methoxy-methylenedioxyamphetamineCategories: Serotonin 5-HT2 Receptor Agonists, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
  8. Drug

    Rivaroxaban

    go.drugbank.com/drugs/DB06228
    ApprovedInvestigational

    However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. … FDA approved on July 1, 2011.

    Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: XARELTO 10 MG FILM KAPLI TABLET, 5 ADET, VOXABAN 10 MG FİLM KAPLI TABLET, 5 ADET
  9. Drug

    Oxaliplatin

    go.drugbank.com/drugs/DB00526
    ApprovedInvestigational

    [A797] Although oxaliplatin has been investigated as a monotherapy, it is typically administered in combination with fluorouracil and leucovorin, known as the FOLFOX regimen, for the treatment of colorectal … Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin.

    Synonyms: (SP-4-2-(1R-TRANS))-(1,2-CYCLOHEXANEDIAMINE-N,N')(ETHANEDIOATO(2-)-O,O')PLATINUM, PLATINUM, ((1R,2R)-1,2-CYCLOHEXANEDIAMINE-.KAPPA.N,.KAPPA.N')(ETHANEDIOATO(2-)-.KAPPA.O1,.KAPPA.O2)-, (SP-4-2)-Categories: OCT2 Substrates with a Narrow Therapeutic Index
  10. Drug

    Flurbiprofen

    go.drugbank.com/drugs/DB00712
    ApprovedInvestigational

    Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity.

    Synonyms: (±)-2-fluoro-α-methyl-4-biphenylacetic acid, 2-(2-fluorobiphenyl-4-yl)propanoic acidMixtures: FULDUO 100 MG/8 MG FİLM KAPLI TABLET, 14 ADET, MULTIFLEX 200/8 MG SR KAPSUL, 14 ADET