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Displaying results 2031 - 2040 of 10000 in total
  1. Drug

    Cochliobolus lunatus

    go.drugbank.com/drugs/DB10933
    Approved

    Cochliobolus lunatus is a fungus which can provoke allergic reactions. Cochliobolus lunatus extract is used in allergenic testing.

  2. Drug

    Haematonectria haematococca

    go.drugbank.com/drugs/DB10934
    Approved

    Haematonectria haematococca is a fungus which can provoke allergic reactions. Haematonectria haematococca extract is used in allergenic testing.

  3. Drug

    Neurospora sitophila

    go.drugbank.com/drugs/DB10969
    Approved

    Neurospora sitophila is a fungus which can provoke allergic reactions. Neurospora sitophila extract is used in allergenic testing.

    Mixtures: Rinkel Mold Mix A
  4. Drug

    Tolvaptan

    go.drugbank.com/drugs/DB06212
    ApprovedInvestigational

    FDA approved on May 19, 2009.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  5. Drug

    Lacosamide

    go.drugbank.com/drugs/DB06218
    ApprovedInvestigational

    Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. … Lacosamide exhibits a stereoselective mode of interaction with sodium channels.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (R)-2-acetamido-N-benzyl-3- methoxypropionamide, (R)-LACOSAMIDE 1
  6. Drug

    Serine

    go.drugbank.com/drugs/DB00133
    ApprovedInvestigationalNutraceutical

    A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids.

    Mixtures: 4.25%travasol Amino Acid InJ.W.elecw.5%dex., 2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.Synonyms: Ser, (S)-2-Amino-3-hydroxypropanoic acid
  7. Drug

    Iophendylate

    go.drugbank.com/drugs/DB01187
    Approved

    In 1942 Van Wagenen (a neurosurgical colleague of Warrens, at the University of Rochester) identified Iophendylate as causing chemical meningitis in 30 patients where "space-displacing masses within the … Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231).

    Synonyms: Ethyl 10-(p-iodophenyl)-undecanoate, Ethyl 10-(p-iodophenyl)undecylateCategories: X-Ray Contrast Media, Iodinated, Non-Watersoluble X-Ray Contrast Media
  8. Drug

    Garetosmab

    go.drugbank.com/drugs/DB16379
    ApprovedInvestigational

    Garetosmab-grts is an activin A inhibitor used to treat fibrodysplasia ossificans progressiva (FOP). … [L63940] It is a fully human IgG4 monoclonal antibody that binds and neutralizes activin A, blocking activin A from activating the mutant ACVR1 receptor that, in FOP, drives the formation of heterotopic

  9. Drug

    Drotaverine

    go.drugbank.com/drugs/DB06751
    ApprovedWithdrawn

    Drotaverine is an antispasmodic drug that works by inhibiting phosphodiesterase-4 (PDE4). … [A231619] It is a benzylisoquinoline derivative that is structurally related to [papaverine], although it displays more potent antispasmodic activities than papaverine.

    Categories: Heterocyclic Compounds, 2-Ring, Phosphodiesterase 4 Inhibitors
  10. Drug

    Ivacaftor

    go.drugbank.com/drugs/DB08820
    ApprovedInvestigational

    , an ion channel involved in the transport of chloride and sodium ions across cell membranes. … [L6814,L6979,L6847] Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide