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Trifarotene
go.drugbank.com/drugs/DB12808ApprovedInvestigationalto vitamin A and are analogous only in function. … as compared to older, less selective retinoids.
Danegaptide
go.drugbank.com/drugs/DB11821InvestigationalDanegaptide has been investigated for the treatment of Focus of Study is STEMI.
Gadopiclenol
go.drugbank.com/drugs/DB17084ApprovedInvestigational[A254002] Gadopiclenol has high kinetic stability and a high r1 relaxivity, allowing it to be used at lower doses than classic extracellular GBCAs. … It is indicated for use with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and the body.
Brexanolone
go.drugbank.com/drugs/DB11859ApprovedInvestigationalAnd finally, although brexanolone may also be undergoing clinical trials to investigate its abilities to treat super-refractory status epilepticus, it appears that some such studies have failed to meet … As of March 2019, brexanolone - developed and made available commercially by Sage Therapeutics Inc. as the brand name product Zulresso - is the first drug to have ever been approved by the US FDA specifically
Synonyms: allopregnan-3α-ol-20-oneDiazepam
go.drugbank.com/drugs/DB00829ApprovedIllicitInvestigationalVet approvedThis current development is subsequently an important addition to the rescue therapy tool chest for patients with epilepsy [L5200].
Synonyms: 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-oneProducts: DIAZEPAM MYLAN GENERICSAmbenonium
go.drugbank.com/drugs/DB01122ApprovedWithdrawnAmbenonium is a cholinesterase inhibitor. It is used in the management of myasthenia gravis.
Raloxifene
go.drugbank.com/drugs/DB00481ApprovedInvestigationalDue to the risk of bone fractures that may lead to morbidities and reduced quality of life, the management of osteoporosis in postmenopausal women with the use of therapeutic agents in addition to concurrent … Due to the decline in estrogen levels in postmenopausal osteoporosis, hormone replacement therapy (HRT), such as estradiol, has been used to ameliorate the condition.
Lumateperone
go.drugbank.com/drugs/DB06077ApprovedInvestigational[A189093] Both characteristics lend to a more favourable adverse effect profile and ultimately safer drug.[A189093,L10908] … [A189093,A189174] The data so far indicates that lumateperone can alleviate both positive and negative symptoms of schizophrenia.
Cobicistat
go.drugbank.com/drugs/DB09065ApprovedInvestigationalMore specifically, cobicistat is indicated to increase systemic exposure of atazanavir or darunavir (once daily dosing regimen) in combination with other antiretroviral agents in the treatment of HIV-1
Copanlisib
go.drugbank.com/drugs/DB12483ApprovedInvestigationalCopanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity against the alpha and delta isoforms. PI3K, a lipid kinase that activates downstream signalling pathways involved in cell surviva...