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Pepsin
go.drugbank.com/drugs/DB13198ApprovedWithdrawnInterestingly, recent research has suggested that pepsin participates in the digestion of nucleic acids [L2391]. … Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, and dairy products [L2358].
Moroctocog alfa
go.drugbank.com/drugs/DB13999Approvedin the 1980s [A31551, A32272, L2177]. … Bleeding can range in severity from minor concerns, such as nosebleeds, to more serious events such as hemorrhaging in the joints, brain, or digestive tract [A32280].
Erenumab
go.drugbank.com/drugs/DB14039ApprovedInvestigationalCGRP receptor, which is believed to play a critical role in migraine [L2823]. … The antibody is produced utlilizing recombinant DNA technology in Chinese hamster ovary cells [FDA Label].
Products: AIMOVIG SOLUTION FOR INJECTION IN PRE-FILLED PEN 70MG/ML, AIMOVIG SOLUTION FOR INJECTION IN PRE-FILLED PEN 140MG/MLLiotrix
go.drugbank.com/drugs/DB01583ApprovedIn fact, administration of T3 may result in supratherapeutic levels of T3. … It is now known that the thyroid gland secretes approximately ten times more T4 than T3 and that 80% of serum T3 is derived from deiodination of T4 in peripheral tissues.
1,2-dichlorobenzene
go.drugbank.com/drugs/DB13963ApprovedWithdrawn1,2-Dichlorobenzene, also named ortho-dichlorobenzene, is an organic compound. It is a non-polar colorless liquid that is miscible in most organic solvents. … insecticide and as an agent to remove carbon-based contamination from metal.
Categories: Compounds used in a research, industrial, or household settingAtaluren
go.drugbank.com/drugs/DB05016ApprovedWithdrawnMore specifically, ataluren is used in the small group of patients whose disease is caused by a specific genetic defect (called a ‘nonsense mutation’) in the dystrophin gene. … Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk.
Vonoprazan
go.drugbank.com/drugs/DB11739ApprovedInvestigational[A253707] In February 2015, vonoprazan was first marketed in Japan for the treatment of acid-related disorders and as an adjunct to _Helicobacter pylori_ (_H. pylori_) eradication. … [A253702] In May 2022, the FDA approved the use of vonoprazan in a co-packaged product containing amoxicillin and clarithromycin for the treatment of _H. pylori_ infection.
Synonyms: 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamineInfluenza A virus A/Brisbane/10/2010 (H1N1) antigen (MDCK cell derived, propiolactone inactivated)
go.drugbank.com/drugs/DB10998ApprovedInvestigationalWithdrawnInactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.
Mixtures: Medical Provider Single Use EZ Flu Shot Flucelvax 2014-2015 Kit, Medical Provider Single Use EZ Flu Shot Flucelvax 2015-2016Daratumumab
go.drugbank.com/drugs/DB09331ApprovedInvestigationalIn July 2024, it was further approved in combination with bortezomib, lenalidomide, and dexamethasone (D-VRd) for induction and consolidation therapy in newly diagnosed, transplant-eligible patients. … [A7935] It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of its kind.
Hydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigational[L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect. … [A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus