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Lucitanib
go.drugbank.com/drugs/DB11845InvestigationalLucitanib has been used in trials studying the treatment of ER+, MBC, SCLC, HER2+, and NSCLC, among others.
Categories: Heterocyclic Compounds, 2-RingBafetinib
go.drugbank.com/drugs/DB11851InvestigationalBafetinib has been used in trials studying the treatment of Adult Gliosarcoma, Adult Mixed Glioma, Adult Glioblastoma, Chronic Myeloid Leukemia, and Acute Lymphocytic Leukemia, among others.
Categories: Heterocyclic Compounds, 1-RingTegobuvir
go.drugbank.com/drugs/DB11852InvestigationalTegobuvir has been investigated for the treatment of Hepatitis C, Chronic.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingRelugolix
go.drugbank.com/drugs/DB11853ApprovedInvestigationalRelugolix is a gonadotropin-releasing hormone (GnRH) receptor antagonist used in the treatment of several hormone-responsive conditions. … [A225761] Relugolix is the first (and currently only) orally-administered GnRH receptor antagonist approved for the treatment of prostate cancer - similar therapies such as [degarelix] require subcutaneous
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesBrexanolone
go.drugbank.com/drugs/DB11859ApprovedInvestigationalAs of March 2019, brexanolone - developed and made available commercially by Sage Therapeutics Inc. as the brand name product Zulresso - is the first drug to have ever been approved by the US FDA specifically … Since PPD, like various other types of depression, is characterized by feelings of sadness, worthlessness or guilt, cognitive impairment, and/or possibly suicidal ideation, it is considered a life-threatening
Categories: Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator, Neuroactive Steroid Gamma-Aminobutyric Acid (GABA) A Receptor Positive ModulatorsAlvelestat
go.drugbank.com/drugs/DB11863InvestigationalAlvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease.
Categories: Heterocyclic Compounds, 1-RingJNJ-39393406
go.drugbank.com/drugs/DB11867InvestigationalJNJ-39393406 has been used in trials studying the treatment and basic science of DEPRESSION, Schizophrenia, Smoking Cessation, Cognition Disorders, and Alzheimer's Disease.
Categories: Heterocyclic Compounds, 1-RingEtiracetam
go.drugbank.com/drugs/DB11868ExperimentalEtiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)).
Categories: Heterocyclic Compounds, 1-RingValspodar
go.drugbank.com/drugs/DB11869InvestigationalValspodar has been used in trials studying the treatment of Cancer, Sarcoma, Leukemia, Lymphoma, and Breast Cancer, among others.
Categories: ATP Binding Cassette Transporter, Subfamily B, Member 1, P-glycoprotein inhibitorsPiromidic acid
go.drugbank.com/drugs/DB13744InvestigationalCategories: Heterocyclic Compounds, 1-Ring