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Displaying results 2051 - 2060 of 10000 in total
  1. Drug

    Chloramphenicol

    go.drugbank.com/drugs/DB00446
    ApprovedInvestigationalVet approvedWithdrawn

    It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. … (From Martindale, The Extra Pharmacopoeia, 29th ed, p106) The FDA has withdrawn all oral drug products containing chloramphenicol, due to the high risk of fatal aplastic anemia associated with this

    Synonyms: D-(−)-threo-1-p-nitrophenyl-2-dichloroacetylamino-1,3-propanediol, D-(−)-2,2-dichloro-N-(β-hydroxy-α-(hydroxymethyl)-p-nitrophenylethyl)acetamideMixtures: CORTIFENOL H POMADA OFTALMICA 4 G, CLOXONA-O
  2. Drug

    Ranitidine

    go.drugbank.com/drugs/DB00863
    ApprovedWithdrawn

    [L10818,F4253] The prevalence of GERD is thought to be 10-20% in western countries. … Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as [cimetidine] and [famotidine].

    Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingProducts: RANITIDINA 50 MG EN SODIO CLORURO 0.7% POR 100 ML (INFUSION), RANOBEL 50 MG/2 ML ENJEKTABL AMPUL, 5 ADET
  3. Drug

    N-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid

    go.drugbank.com/drugs/DB04057
    Experimental

    Synonyms: N-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid, β-DADF, MSA, multisubstrate adduct inhibitor
  4. Drug

    Fentanyl

    go.drugbank.com/drugs/DB00813
    ApprovedIllicitInvestigationalVet approved

    Fentanyl's high potency has also made it a common adulterant in illicit drugs, especially heroin. … [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose deaths).[L6748] Opioid overdoses kill an average of 11 Canadians daily.

    Synonyms: 1-phenethyl-4-N-propionylanilinopiperidine, 1-Phenethyl-4-(N-phenylpropionamido)piperidineCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitors
  5. Drug

    Loratadine

    go.drugbank.com/drugs/DB00455
    ApprovedInvestigational

    Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.

    Mixtures: Clarinase 5 mg/ 120 mg Retardtabletten, LIQUICAPS 60 MG CAPSULA BLANDACategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitors
  6. Drug

    Nifedipine

    go.drugbank.com/drugs/DB01115
    ApprovedInvestigational

    Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to [nicardipine].

    Synonyms: 4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsäuredimethylesterMixtures: NIF TEN 50
  7. Drug

    KAND567

    go.drugbank.com/drugs/DB16511
    Investigational

    Because COVID-19 involves cytotoxic cells associated with this pathway, KAND567 is currently being tested as a treatment for those with the illness[L32908]. … KAND567, a small molecule, blocks the fractaline (CX3CL1) receptor, which mediates the immune system response to inflammation[L32908].

    Categories: Experimental Unapproved Treatments for COVID-19Synonyms: 1-Pentanol, 2-[[2-aMino-5-[[(1S)-1-phenylethyl]thio]thiazolo[4,5-d]pyriMidin-7-yl]aMino]-4-Methyl-, (2R)-
  8. Drug

    Butylscopolamine

    go.drugbank.com/drugs/DB09300
    ApprovedInvestigationalVet approved

    It is not a pain medication in the normal sense, since it does not directly affect pain, but rather works to prevent painful cramps and spasms from occurring. … It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.

    Synonyms: N-butylscopolammonium, N-butylscopolammonium ionMixtures: DIPIRONA 2.5 G + HIOSCINA 20 MG/5 ML SOLUCION INYECTABLE, DIPIRONA 2.5 G + HIOSCINA 20 MG/5 ML SOLUCION INYECTABLE
  9. Drug

    Fenofibrate

    go.drugbank.com/drugs/DB01039
    ApprovedInvestigational

    Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil].[A185954] Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.

    Synonyms: 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester, Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionateMixtures: SIMITRI® 145/40 MG, STAFEN 135/10 MG CAPSULAS
  10. Drug

    Rifamycin

    go.drugbank.com/drugs/DB11753
    ApprovedInvestigationalWithdrawn

    Product which allowed it to have a status a priority review. … Falk Pharma Gmbh and it was granted a waiver for the tested conditions.[L4801]

    Mixtures: RIFOCIN 125 MG+5 MG/1,5 ML IM ENJEKSİYON İÇİN SOLÜSYON İÇEREN AMPUL, 100 ADET, RIFOCIN 125 MG+5 MG/1,5 ML IM ENJEKSİYON İÇİN SOLÜSYON İÇEREN AMPUL, 1 ADETCategories: MATE 1 Inhibitors, P-glycoprotein inhibitors