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Displaying results 2061 - 2070 of 2158 in total
  1. Drug

    Delandistrogene moxeparvovec

    go.drugbank.com/drugs/DB16802
    ApprovedInvestigational

    [L47026] DMD is an X-linked genetic disorder characterized by mutations in the dystrophin gene, leading to a deficiency in functional dystrophin protein.

  2. Drug

    Becotatug vedotin

    go.drugbank.com/drugs/DB17407
    Investigational

    MRG-003 is a recombinant humanized anti-human epidermal growth factor receptor monoclonal antibody conjugated to monomethyl auristatin E.

  3. Drug

    Tividenofusp alfa

    go.drugbank.com/drugs/DB17628
    ApprovedInvestigational

    Hunter syndrome is a rare, X-linked lysosomal storage disorder caused by a deficiency in the enzyme iduronate-2-sulfatase (IDS), which leads to the toxic accumulation of glycosaminoglycans (GAGs) throughout

    Synonyms: - L-iduronate sulfate sulfatase, EC:3.1.6.13) pro-protein (1-525), fused via the peptide linker 526 GGGGS 530 to a human immunoglobulin G1 C-terminal Fc fragment (531-757) variant (L 544>A, L 545>A, T
  4. Drug

    AEM-28

    go.drugbank.com/drugs/DB17642
    Investigational

    AEM-28 is a 28 amino acid mimetic of apolipoprotein E being investigated for lipid disorders, such as homozygous familial hypercholesterolemia. It possesses anti-inflammatory properties.[A258764]

  5. Drug

    Acimtamig

    go.drugbank.com/drugs/DB18674
    Investigational

    Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct.

    Synonyms: AFM13 (ANTI CD30 X ANTI CD16), tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct
  6. Drug

    RC88

    go.drugbank.com/drugs/DB18697
    Experimental

    RC88 is an antibody-drug conjugate comprising a humanized anti-mesothelin monoclonal antibody conjugated to monomethyl auristatin E (MMAE).

  7. Drug

    TrenibotulinumtoxinE

    go.drugbank.com/drugs/DB19082
    Approved

    [L64118] It is the first and only rapid-onset, short-duration botulinum neurotoxin serotype E approved in Europe.[L64118] … TrenibotulinumtoxinE is a botulinum neurotoxin serotype E, produced in *Clostridium botulinum*, used for the temporary improvement in the appearance of moderate to severe glabellar lines in adults.

    Synonyms: BOTULINUM NEUROTOXIN SEROTYPE E (BONT/E) (EB-001), BONTOXILYSIN-E
  8. Drug

    Meteneprost

    go.drugbank.com/drugs/DB19692
    Experimental

    Meteneprost is a small molecule drug. Meteneprost has a monoisotopic molecular weight of 378.28 Da.

    Categories: Prostaglandins E, Synthetic
  9. Drug

    Vatinoxan

    go.drugbank.com/drugs/DB19781
    Experimental

    The usage of the INN stem '-oxan(e)' in the name indicates that Vatinoxan is a benzodioxane derivative. Vatinoxan has a monoisotopic molecular weight of 418.17 Da.

  10. Drug

    Flesinoxan

    go.drugbank.com/drugs/DB19853
    Experimental

    The usage of the INN stem '-oxan(e)' in the name indicates that Flesinoxan is a benzodioxane derivative. Flesinoxan has a monoisotopic molecular weight of 415.19 Da.