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Displaying results 2081 - 2090 of 10000 in total
  1. Drug

    ABT-737

    go.drugbank.com/drugs/DB17023
    Experimental

    An inhibitor of members of the Bcl‑2 family of apoptosis regulators.[A252977]

    Categories: Proto-Oncogene Proteins c-bcl-2, Heterocyclic Compounds, 1-RingSynonyms: Benzamide, 4-(4-((4'-chloro(1,1'-biphenyl)-2-yl)methyl)-1-piperazinyl)-n-((4-(((1r)-3-(dimethylamino)-1-((phenylthio)methyl)propyl)amino)-3-nitrophenyl)sulfonyl)-
  2. Drug

    Narmafotinib

    go.drugbank.com/drugs/DB18463
    Investigational

    Synonyms: 2-(2-(2-((2-methoxy-4-(1-methyl-4-piperidinyl)phenyl)amino)-5-(trifluoromethyl)-4-pyrimidinyl)ethyl)benzeneacetamide, Benzeneacetamide, 2-(2-(2-((2-methoxy-4-(1-methyl-4-piperidinyl)phenyl)amino)-5-(trifluoromethyl)-4-pyrimidinyl)ethyl)-
  3. Drug

    2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol

    go.drugbank.com/drugs/DB13869
    Experimental

    TIMBD is an azaresveratrol analog.

    Synonyms: 2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol, 2-Methoxy-6-[[(4-methylphenyl)imino]methyl]phenol
  4. Drug

    Dersimelagon

    go.drugbank.com/drugs/DB18007
    Investigational

    Synonyms: 1-(2-((3s,4r)-1-((3r,4r)-1-cyclopentyl-3-fluoro-4-(4-methoxyphenyl)pyrrolidine-3-carbonyl)-4-(methoxymethyl)pyrrolidin-3-yl)-5-(trifluoromethyl)phenyl)piperidine-4-carboxylic acid, 4-piperidinecarboxylic acid, 1-(2-((3s,4r)-1-(((3r,4r)-1-cyclopentyl-3-fluoro-4-(4-methoxyphenyl)-3-pyrrolidinyl)carbonyl)-4-(methoxymethyl)-3-pyrrolidinyl)-5- (trifluoromethyl)phenyl)-
  5. Drug

    Brensocatib

    go.drugbank.com/drugs/DB15638
    Approved

    [A274348] Brensocatib is a first-in-class dipeptidyl peptidase 1 (DPP1) inhibitor that inhibits neutrophil serine proteases, addressing a key driver of this inflammation. … [A274348,A274343] It reduces exacerbations and slows lung function decline, offering a targeted approach to managing NCFB.

    Synonyms: (S)-N-((S)-1-Cyano-2-(4-(3-methyl-2-oxo-2,3-dihydrobenzo-(d)oxazol-5-yl)phenyl)ethyl)-1,4-oxazepane-2-carboxamideCategories: MATE 1 Inhibitors, MATE 2 Inhibitors
  6. Drug

    Etacrynic acid

    go.drugbank.com/drugs/DB00903
    ApprovedInvestigational

    A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. … This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.

    Synonyms: (2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)acetic acidCategories: Increased Diuresis at Loop of Henle
  7. Drug

    5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid

    go.drugbank.com/drugs/DB04583
    Experimental

    Synonyms: 5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid
  8. Drug

    9-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-Amine

    go.drugbank.com/drugs/DB03899
    Experimental

    Synonyms: 9-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-Amine
  9. Drug

    2',4'-Dinitrophenyl-2deoxy-2-Fluro-B-D-Cellobioside

    go.drugbank.com/drugs/DB04086
    Experimental

    Synonyms: 2',4'-Dinitrophenyl-2deoxy-2-Fluro-B-D-Cellobioside
  10. Drug

    3-Nitro-4-(2-Oxo-Pyrrolidin-1-Yl)-Benzenesulfonamide

    go.drugbank.com/drugs/DB04394
    Experimental

    Synonyms: 3-Nitro-4-(2-Oxo-Pyrrolidin-1-Yl)-Benzenesulfonamide