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Pralatrexate
go.drugbank.com/drugs/DB06813ApprovedInvestigational[A246703] Pralatrexate was approved by the FDA on September 24, 2009. … [A246693] Pralatrexate is designed to have a higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and is upregulated by oncogenes.
Synonyms: (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid, N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acidBeroctocog alfa
go.drugbank.com/drugs/DB14473ApprovedInvestigationalProducts: DRIED FACTOR VIII FRACTION 500 UI + FACTOR DE VON WILLEBRAND 800 UI, FACTOR VIII DE COAGULACION HUMANO 500 UIPeginterferon beta-1a
go.drugbank.com/drugs/DB09122ApprovedInvestigationalSymptoms may include but are not limited to fatigue, gait changes, bowel or bladder dysfunction, abnormal muscle twitching, vision disturbance, and depressing or mood swings. … It was originally approved by the FDA in 2014 for subcutaneous use, and was approved for intramuscular use in January 2021.
Products: PLEGRIDY®94 UG SOLUCIÓN INYECTABLE.Tepilamide fumarate
go.drugbank.com/drugs/DB18804InvestigationalSynonyms: (n,n-diethylcarbamoyl)methyl methyl (2e)-but-2-ene-1,4-dioate, 2-(diethylamino)-2-oxoethyl and methyl (2e)-but-2-enedioatePegaspargase
go.drugbank.com/drugs/DB00059ApprovedInvestigational[A255912,A255917] In February 1994, pegaspargase was approved by the FDA for the treatment of ALL in patients with hypersensitivity to native forms of L-asparaginase.[A255927] … However, leukemia cells have low levels of this enzyme and depend on exogenous sources. Therefore, the use of pegaspargase results in leukemic cell death.
Products: ONCASPAR ®3750 UI, ONCASPAR® 750 U/ML POLVO PARA SOLUCIÓN INYECTABLECetirizine
go.drugbank.com/drugs/DB00341ApprovedInvestigationalThe prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and up to 30%, according to self-reported nasal symptoms. … Furthermore, some antihistamine agents that are used to treat this condition cause undesirable, sedating effects [A175060].
Mixtures: VERACETAM NF CAPSULAS, Up and Up all day allergy relief dCategories: Histamine H1 Antagonists, Non-SedatingAcebutolol
go.drugbank.com/drugs/DB01193ApprovedInvestigationalA cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. … The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Synonyms: N-(3-acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl)butanamide, N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamideProducts: Nu-acebutolol - Tab 100mg, Nu-acebutolol - Tab 400mgAsparaginase Escherichia coli
go.drugbank.com/drugs/DB00023ApprovedInvestigationalTherapeutic L-asparaginase from _E. coli_ works by depleting the levels of non-essential amino acid, asparagine, in lymphoblastic leukemic cells thus promoting apoptotic cell death [A31999]. … Asparaginase derived from _Escherichia coli_ (L-asparagine amidohydrolase, EC 3.5.1.1) is an enzyme responsible for the metabolism of L-asparagine, by catalyzing L-asparagine into L-aspartic acid and ammonia
Products: KIDROLASE 10000 UIAlfacalcidol
go.drugbank.com/drugs/DB01436ApprovedInvestigationalNutraceuticalAlfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones. … Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of [vitamin D].
Products: ALFACALCIDOL HEXAL 1 UG, ALFACALCIDOL HEXAL 0.5 UGTriclosan
go.drugbank.com/drugs/DB08604ApprovedAn aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group.
Mixtures: QV FLARE UP BATH OIL, QV Flare Up Bath OilProducts: Lysol No Touch, Up (and) Up Green Apple Scent