Acebutolol is a selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults. A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors.
- Mechanism
- Curator reviewed
Acebutolol is a selective β1-receptor antagonist. Activation of β1-receptors by epinephrine increases the heart rate and the blood pressure, and the heart consumes more oxygen. Acebutolol blocks these receptors, lowering the heart rate and blood pressure. This drug then has the reverse effect of epinephrine. In addition, beta blockers prevent the release of renin, which is a hormone produced by the kidneys which leads to constriction of blood vessels.
- Primary indication
- For the management of hypertension and ventricular premature beats in adults.Curator reviewed · 4 structured indications
- Formula / weight
- C18H28N2O4 · 336.4259 g/mol (avg)
- First approval
- Canada, 1997 · United States, 1984
- Brand names
Resolves to
GOEMGAFJFRBGGG-UHFFFAOYSA-NSMILESCCCC(=O)NC1=CC=C(OCC(O)CNC(C)C)C(=C1)C(C)=OWhat you can answer from here — as of September 23, 2026
Which drugs share a target with Acebutolol, and which of those have an active Phase 3 trial?
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