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Ascorbic acid
go.drugbank.com/drugs/DB00126ApprovedInvestigationalNutraceuticalA six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. … Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
Synonyms: Vitamin C, Vitamin-CMixtures: JET-C 400/250 MG EFERVESAN TABLET, 10 ADET, DAYCOLD-HOT 500/10/15/100 MG SAŞE ,10 SAŞEFerric cation
go.drugbank.com/drugs/DB13949ApprovedWithdrawnIron is a transition metal with a symbol Fe and atomic number 26. By mass, it is the most common element on Earth. … deficiency may be characterized without the development of anemia, and may result in functional impairments affecting cognitive development and immunity mechanisms, as well as infant or maternal mortality if it
Synonyms: iron(3+)Mixtures: MALTOFER FOL 100 MG/0.35 MG TABLET, 30 ADET, FERIMAX FORT ÇİĞNEME TABLETİ, 30 ADETTreprostinil
go.drugbank.com/drugs/DB00374ApprovedInvestigationalHowever, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room temperature. … [L41855,L41860,L41865] It reduces symptoms in patients with pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease.
Categories: Prostaglandins I, Cytochrome P-450 SubstratesProducts: TIMERAXONE ® 10 MG/ML, REMODULIN ® INYECCIÓN 10 MG / MLTapentadol
go.drugbank.com/drugs/DB06204ApprovedInvestigationalTapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake. … [A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011.
Synonyms: 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol, PHENOL, 3-((1R,2R)-3-(DIMETHYLAMINO)-1-ETHYL-2-METHYLPROPYL)-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesGuaifenesin
go.drugbank.com/drugs/DB00874ApprovedInvestigationalVet approvedRegardless, on March 1, 2007, the FDA received a petition asking the FDA to notify the public that some antitussives, expectorants, decongestants, antihistamines, and cough/cold combinations are not known … Although it is principally believed that guaifenesin elicits an action to facilitate productive cough to manage chest congestion [A177661, L6100, F4516, F4522, F4525], it is not known whether the agent
International brands: Duratuss GMixtures: BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML, RINOGEST EKSPEKTORAN 30 MG / 5 ML + 100 MG / 5 ML ŞURUP, 150 MLZidovudine
go.drugbank.com/drugs/DB00495ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. … It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS.
Mixtures: COMBİVİR 150 MG/300 MG FİLM KAPLI TABLET, LAMIVUDINA 150 MG & ZIDOVUDINA 300 MG TABLETASCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesSibutramine
go.drugbank.com/drugs/DB01105ApprovedIllicitWithdrawnIt is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States. … In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: OBESTOPPOR 5 MG CAPSULAS, OBESTOP® 10 MG CAPSULASFexofenadine
go.drugbank.com/drugs/DB00950ApprovedInvestigational[L4269] It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation … [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a racemic mixture in which both enantiomers display approximately equivalent antihistamine activity.
Synonyms: 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acidMixtures: Allegra D-12 Hour, Allegra D-12 HourVortioxetine
go.drugbank.com/drugs/DB09068ApprovedInvestigationalreceptor, an agonist of 5-HT1A, and an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors. … It is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin
Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT1 Receptor AgonistsProducts: BRINTELLIX® 10 MG, BRINTELLIX 10 MG FILM KAPLI TABLET ,56 TABLETRifampin
go.drugbank.com/drugs/DB01045ApprovedInvestigationalRifampin, also known as rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and clinically used in 1968.
Synonyms: 3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV, 5,6,9,17,19,21-Hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione 21-acetateMixtures: RIFAMPICIN 75 MG/ISONIAZID 50 MG/PYRAZINAMIDE 150 MG, RIFAMPICIN 75 MG/ISONIAZID 50 MG