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Spinosad
go.drugbank.com/drugs/DB08823ApprovedVet approvedSpinosad has also been experimented for use in cats for treatment of flea infestations, and has also been experimented for use against the KS1 Ctenocephalides felis flea strain infesting dogs, in addition … to many investigations for use in other animals and agricultural plants.
Mixtures: Comfortis Plus (Spinosad + Milbemycin oxime) Chewable Tablets for Dogs 9.1-18kg, Comfortis Plus (Spinosad + Milbemycin oxime) Chewable Tablets for Dogs 18.1-27kgCategories: Compounds used in a research, industrial, or household settingPenicillamine
go.drugbank.com/drugs/DB00859ApprovedInvestigationalThe pharmaceutical form is D-penicillamine, as L-penicillamine is toxic (it inhibits the action of pyridoxine).
Categories: Compounds used in a research, industrial, or household settingOmaveloxolone
go.drugbank.com/drugs/DB12513ApprovedInvestigational[L45424] The EMA approved this drug the following year, in February 2024, and Health Canada in March 2025 for the same condition. … [A257529] In February 2023, omaveloxolone was approved by the FDA for the treatment of Friedreich's ataxia in adults and adolescents aged 16 years and older.
Loracarbef
go.drugbank.com/drugs/DB00447ApprovedWithdrawnLoracarbef is a carbacephem antibiotic sometimes grouped together with the second-generation cephalosporin antibiotics. It is marketed under the trade name Lorabid.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseGALE-301
go.drugbank.com/drugs/DB17262InvestigationalIt is made up of E39, an immunogenic peptide derived from the folate binding protein (FBP), and an immune adjuvant, granulocyte macrophage-colony stimulating factor (GM-CSF).[A254696,L44166,L44171] … GALE-301 is an investigational cancer immunotherapy.
Talquetamab
go.drugbank.com/drugs/DB16678ApprovedInvestigational[A260890] The Committee for Medicinal Products for Human Use (CHMP) of the EMA recommended conditional marketing authorization for talquetamab for the treatment of relapsed or refractory multiple myeloma … It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain.
Phosphatidyl serine
go.drugbank.com/drugs/DB00144ApprovedNutraceuticalThis is part of the process by which the cell is targeted for phagocytosis. PS has been shown to slow cognitive decline in animal models. … The dietary supplement was originally processed from bovine sources however Prion disease scares in the 1990s outlawed this process, and a soy-based alternative was adopted.
Unoprostone
go.drugbank.com/drugs/DB06826ApprovedWithdrawnUnoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate....
Potassium cation
go.drugbank.com/drugs/DB01345ApprovedThe ability of cells to produce electrical discharge is critical for body functions such as neurotransmission, muscle contraction, and heart function. … The balance between potassium and sodium is maintained by ion pumps in the cell membrane.
Categories: Potassium SaltDesipramine
go.drugbank.com/drugs/DB01151ApprovedIn non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, desipramine exerts a positive effect on mood. … See toxicity section below for a complete listing of side effects.
Categories: Antidepressive Agents Indicated for Depression