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Displaying results 2141 - 2150 of 10000 in total
  1. Drug

    Ripertamab

    go.drugbank.com/drugs/DB16314
    Investigational

    Ripertamab is under investigation in clinical trial NCT02772822 (A Study Comparing the Efficiency and Safety of S-chop(cyclophosphamide, Hydroxydaunomycin, Oncovin, and Prednisone) Versus R-CHOP in Untreated

    Synonyms: Immunoglobulin g1-kappa, anti-(homo sapiens ms4a1 (membrane-spanning 4-domains subfamily a member 1, cd20)), chimeric monoclonal antibody, Immunoglobulin igg1, anti-(human cd20 antigen) (human-mus musculus monoclonal disulfide sct400 .gamma.1-chain), disulfide with human-mus musculus monoclonal sct400 .kappa.-chain, dimer
  2. Drug

    NM-004

    go.drugbank.com/drugs/DB18066
    Experimental

    Synonyms: 5-((e)-(4-(carboxymethyl)phenyl)azo)-2-hydroxy-benzoic acid, Benzeneacetic acid, 4-(2-(3-carboxy-4-hydroxyphenyl)diazenyl)-
  3. Drug

    Phosphopantothenic acid

    go.drugbank.com/drugs/DB16966
    Experimental

    Synonyms: -alanine, n-((2r)-2-hydroxy-3,3-dimethyl-1-oxo-4-(phosphonooxy)butyl)-, 4'-phospho-d-pantothenic acid
  4. Drug

    Danicopan

    go.drugbank.com/drugs/DB15401
    ApprovedInvestigational

    [A263501,L50411] Danicopan is a small molecule complement factor D inhibitor that selectively blocks the alternative pathway, thereby working to address extravascular hemolysis when used in conjunction … [L50381] It was first approved in January 2024 in Japan for patients with PNH,[A263506,L50416] shortly after which the EMA adopted a positive opinion and recommended granting it marketing authorization

    Synonyms: (2S,4R)-1-(2-(3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl)acetyl)-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine-2-carboxamide, (2S,4R)-1-(2-(3-acetyl-5-(2-methylpyrimidine-5-yl)-1H-indazol-1-yl)acetyl)-N-(6-bromopyridine-2-yl)-4-fluoropyrrolidine-2-carboxamideCategories: P-glycoprotein inhibitors, Complement Factor D Inhibitor
  5. Drug

    (R)-methylmalonyl-CoA

    go.drugbank.com/drugs/DB04045
    Investigational

    Categories: Thioesters of coenzyme A, Heterocyclic Compounds, 2-RingSynonyms: Methylmalonyl-coenzyme A, (R)-2-Methyl-3-oxopropanoyl-CoA
  6. Drug

    CYNK-101

    go.drugbank.com/drugs/DB18637
    Investigational

    CYNK-101 is an allogeneic human placental hematopoietic stem cell-derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP).

    Synonyms: allogeneic human placental hematopoietic stem cell derived natural killer (NK) cell therapy product that is genetically modified to express a variant of CD16 (CD16VP)
  7. Drug

    Paxamate

    go.drugbank.com/drugs/DB19699
    Experimental

    Paxamate is a small molecule drug. Paxamate has a monoisotopic molecular weight of 227.09 Da.

    Synonyms: 4-biphenylyl methylcarbamate
  8. Drug

    Hydroxystenozole

    go.drugbank.com/drugs/DB20040
    Experimental

    Hydroxystenozole is a small molecule drug. Hydroxystenozole has a monoisotopic molecular weight of 326.24 Da.

    Synonyms: 4-dehydrostanozolol
  9. Drug

    Tiformin

    go.drugbank.com/drugs/DB20697
    Experimental

    Tiformin is a small molecule drug. Tiformin has a monoisotopic molecular weight of 144.1 Da.

    Synonyms: 4-guanidinobutyramide
  10. Drug

    Ximelagatran

    go.drugbank.com/drugs/DB04898
    ApprovedWithdrawn

    Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former. … In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue its distribution in countries

    Synonyms: ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin-1-yl]- 2-oxo-ethyl]amino]acetateCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring