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Displaying results 2151 - 2160 of 2250 in total
  1. Drug

    Uproleselan

    go.drugbank.com/drugs/DB14829
    Investigational

    Uproleselan is a novel, specific E-Selectin antagonist under investigation in clinical trial NCT02306291 (Study to Determine Safety, Pharmacokinetics and Efficacy of GMI-1271 in Combination With Chemotherapy

    Categories: E-Selectin, antagonists & inhibitors
  2. Drug

    Cefiderocol

    go.drugbank.com/drugs/DB14879
    ApprovedInvestigational

    supported by a positive clinical trial composed of 448 patients with complicated urinary tract infections which demonstrated a 72.6% rate of symptom resolution and bacterial eradication with cefiderocol compared

  3. Drug

    Tepotinib

    go.drugbank.com/drugs/DB15133
    ApprovedInvestigational

    Tepotinib is a MET tyrosine kinase inhibitor intended to treat a variety of MET-overexpressing solid tumors. It was originally developed in partnership between EMD Serono and the University of Texas M.D. Anderson Cancer Center in 2009 an...

  4. Drug

    Avapritinib

    go.drugbank.com/drugs/DB15233
    ApprovedInvestigational

    Avapritinib, or BLU-285, is a selective tyrosine kinase inhibitor of KIT and platelet derived growth factor receptor alpha indicated for the treatment of unresectable, metastatic gastrointestinal stromal tumors and advanced systemic mast...

  5. Drug

    Kanamycin

    go.drugbank.com/drugs/DB01172
    ApprovedInvestigationalVet approvedWithdrawn

    Kanamycin (also known as kanamycin A) is an aminoglycoside bacteriocidal antibiotic, available in oral, intravenous, and intramuscular forms, and used to treat a wide variety of infections. Kanamycin is isolated from the bacterium Strept...

  6. Drug

    Iophendylate

    go.drugbank.com/drugs/DB01187
    Approved

    Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231). Iophendylate, which was never shown to be safe, was initially...

    Categories: X-Ray Contrast Media, Iodinated, Non-Watersoluble X-Ray Contrast Media
  7. Drug

    Potassium cation

    go.drugbank.com/drugs/DB01345
    Approved

    Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells. The concentration differences of these charged particles causes a difference in electric potential between the insid...

    Mixtures: Telom-X-gene
  8. Drug

    Glycolic acid

    go.drugbank.com/drugs/DB03085
    Approved

    Mixtures: Triple X-Lotion
  9. Drug

    Meteneprost

    go.drugbank.com/drugs/DB19692
    Experimental

    Meteneprost is a small molecule drug. Meteneprost has a monoisotopic molecular weight of 378.28 Da.

    Categories: Prostaglandins E, Synthetic
  10. Drug

    Vatinoxan

    go.drugbank.com/drugs/DB19781
    Experimental

    The usage of the INN stem '-oxan(e)' in the name indicates that Vatinoxan is a benzodioxane derivative. Vatinoxan has a monoisotopic molecular weight of 418.17 Da.