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Acipimox
go.drugbank.com/drugs/DB09055ApprovedInvestigationalAcipimox inhibits the production of triglycerides by the liver and the secretion of VLDL, which leads indirectly to a modest reduction in LDL and increase in HDL. … High doses can cause disorders of liver function, impair glucose tolerance and precipitate gout.
Products: OLBETAM CAPSULE 250 mgOsimertinib
go.drugbank.com/drugs/DB09330ApprovedInvestigationalof life. … Approximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs due to the presence of specific activating EGFR mutations within the tumour cells.
Products: TAGRISSO® 40 MG, TAGRISSO® 80 MG.Sipavibart
go.drugbank.com/drugs/DB21908ApprovedInvestigational[A274088] Sipavibart is approved for the pre-exposure prophylaxis treatment of COVID-19 in immunocompromised patients.[L53418]
Sodium aurothiomalate
go.drugbank.com/drugs/DB09276ApprovedWithdrawnIt is most effective in active progressive rheumatoid arthritis and of little or no value in the presence of extensive deformities or in the treatment of other forms of arthritis. … Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL.
Products: MIOCRIN 50 MG, MYOCRISIN INJECTION 20 MG (4% W/V)Doxylamine
go.drugbank.com/drugs/DB00366ApprovedInvestigationalVet approvedHistamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Mixtures: DG Health Tussin, PRİLAM DR 10 MG/10 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 ADETProducts: Dg Health Sleep Aid, UNISOM 25 MG TABLET, 20 ADETOlaparib
go.drugbank.com/drugs/DB09074ApprovedInvestigational[L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell … Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2.
Products: LYNPARZA® 100 MG, LYNPARZA® 150 MGTirzepatide
go.drugbank.com/drugs/DB15171ApprovedInvestigational[A246260] Its protein sequence was based on the sequence of endogenous GIP, and its pharmacological action on GLP-1 receptors is comparable to endogenous GIP; however, the long half-life of tirzepatide … [L48766] On September 15, 2022, tirzepatide was also approved by the European Commission.[L44386]. On November 02, 2023, tirzepatide was also approved by the Health Canada [L52800]
Categories: Receptors, G-Protein-CoupledProducts: Mounjaro 5 mg solution for injection in vial, Mounjaro 10 mg solution for injection in vialMoxonidine
go.drugbank.com/drugs/DB09242ApprovedInvestigationalWithdrawnAs well, moxonidine has been shown to present blood pressure-independent beneficial effects on insulin resistance syndrome. … Moxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension.
Products: MOXONIDINA EG, Normohex 0,2 mg - FilmtablettenTemazepam
go.drugbank.com/drugs/DB00231Approvedand approved later on. … Regardless, temazepam has become one of the most frequently prescribed medications internationally and sees millions of prescriptions every year.
Products: TEMAZEP - CT 10 MG KAPSELNAcetic acid
go.drugbank.com/drugs/DB03166ApprovedInvestigationalAcetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. … (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or fungus.
Mixtures: Selectbag One (ax 225 G), Selectbag One (ax 325 G)Categories: Compounds used in a research, industrial, or household setting