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Linaclotide
go.drugbank.com/drugs/DB08890ApprovedInvestigationalLinaclotide is a synthetic 14-amino acid cyclic peptide [A260271] and first-in-class guanylate cyclase-C (G-CC) agonist. … [A260276] It is also a homolog of a heat-stable enterotoxin derived from _Escherichia coli_, the first natural ligand that activates GC-C.
Synonyms: -GLUTAMYL-L-TYROSYL-L-CYSTEINYL-L-CYSTEINYL-L-ASPARAGINYL-L-PROLYL-L-ALANYL-L-CYSTEINYL-L-THREONYLGLYCYL-L-CYSTEINYL-, CYCLIC (1->6),(2->10),(5->13)-TRIS(DISULFIDE), L-TYROSINE, L-CYSTEINYL-L-CYSTEINYL-L-.ALPHA.Categories: Guanylate Cyclase-C Agonist, Guanylyl Cyclase C AgonistsFlunarizine
go.drugbank.com/drugs/DB04841ApprovedInvestigationalFlunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity.
Synonyms: 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazineCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingIsoprenaline
go.drugbank.com/drugs/DB01064ApprovedInvestigational[A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and a stronger action than [adrenaline]. … Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion
Synonyms: 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanol, 1-(3,4-dihydroxyphenyl)-2-isopropylaminoethanolInternational brands: Proternol L5-QUINOXALIN-6-YLMETHYLENE-THIAZOLIDINE-2,4-DIONE
go.drugbank.com/drugs/DB04769ExperimentalSynonyms: 5-QUINOXALIN-6-YLMETHYLENE-THIAZOLIDINE-2,4-DIONE(5S)-5-Iododihydro-2,4(1H,3H)-pyrimidinedione
go.drugbank.com/drugs/DB02303ExperimentalSynonyms: (5S)-5-Iododihydro-2,4(1H,3H)-pyrimidinedione5-monophosphate-9-beta-D-ribofuranosyl xanthine
go.drugbank.com/drugs/DB02309ExperimentalSynonyms: 5-monophosphate-9-beta-D-ribofuranosyl xanthineNicotinamide-adenine-dinucleotide-5-hydroxy-4-oxonorvaline
go.drugbank.com/drugs/DB02349ExperimentalSynonyms: Nicotinamide-adenine-dinucleotide-5-hydroxy-4-oxonorvaline7-Methyl-7,8-dihydroguanosine 5'-(dihydrogen phosphate)
go.drugbank.com/drugs/DB04259ExperimentalSynonyms: 7-Methyl-7,8-dihydroguanosine 5'-(dihydrogen phosphate)3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate
go.drugbank.com/drugs/DB04366ExperimentalSynonyms: 3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE
go.drugbank.com/drugs/DB08510ExperimentalSynonyms: 5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE