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Belumosudil
go.drugbank.com/drugs/DB16703ApprovedInvestigationalBelumosudil is used in the treatment of chronic graft-versus-host disease (GVHD) and has been investigated for the treatment of pulmonary arterial hypertension. It is an inhibitor of rho-associated coiled-coil-containing protein kinases ...
Azficel-T
go.drugbank.com/drugs/DB11051ApprovedWithdrawnAzficel-T is an autologous cellular product composed of fibroblasts indicated for improvement of the appearance of moderate to severe nasolabial fold wrinkles in adults. Dermal fibroblasts are collected from the post-auricular biopsy tis...
Mitapivat
go.drugbank.com/drugs/DB16236ApprovedInvestigationalMitapivat is a novel, first-in-class pyruvate kinase activator. It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival of red blood cells. Defects in the pyruvate kinase enzyme in various ...
Methenamine
go.drugbank.com/drugs/DB06799ApprovedInvestigationalVet approvedMethenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of meth...
Mixtures: Urin D/S, Prosed/DSEfalizumab
go.drugbank.com/drugs/DB00095ApprovedWithdrawnIt was later withdrawn in 2009 due to a potential risk of progressive multifocal leukoencephalopathy (PML).[L43797]
Aminophenazone
go.drugbank.com/drugs/DB01424ApprovedWithdrawnThe FDA suspended the use of aminophenazone due to its association with agranulocytosis, a life-threatening side effect.[A254242,L43942]
AV-COVID-19
go.drugbank.com/drugs/DB15802InvestigationalThe monocytes are then differentiated in vitro into dendritic cells with IL-4 and GM-CSF, incubated with SARS-CoV-2 antigens prior to administration.
Synonyms: DC-ATAGSK-1521498
go.drugbank.com/drugs/DB12886InvestigationalGSK1521498 has been used in trials studying the treatment of Obesity and Alcoholism.
Categories: Receptors, Opioid, muBismuth subgallate
go.drugbank.com/drugs/DB13909ApprovedBismuth subgallate is a yellow colored substance that presents as an odorless powder that undergoes discoloration when exposed to sunlight. It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed. Possessing ...